SCHEMBL11375673

SCHEMBL11375673

CCc1noc(-c2cccc(C(F)(F)F)c2)c1C(=O)O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IP6K1 Q92551 1/20 0.55
IP6K3 Q96PC2 1/20 0.55
IP6K2 Q9UHH9 1/20 0.55
RXRA P19793 1/20 0.45
RXRB P28702 1/20 0.45
RXRG P48443 1/20 0.45
ALDH1A1 P00352 3/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
XDH P47989 1/20 0.44
PIN1 Q13526 1/20 0.44
KMO O15229 2/20 0.43
MEN1 O00255 3/20 0.43
KMT2A Q03164 3/20 0.43
NPC1 O15118 1/20 0.43
RAB9A P51151 1/20 0.43
GPBAR1 Q8TDU6 1/20 0.43
S1PR1 P21453 2/20 0.42
BRD4 O60885 1/20 0.41
TRPV1 Q8NER1 2/20 0.41
HPGD P15428 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10665627 0.85 TRPV1 (0.55) MEN1KMT2ATRPV1MAPT
SCHEMBL11375484 0.84 IP6K1 (0.58) IP6K1IP6K3IP6K2RXRARXRB
SCHEMBL11377985 0.81 PTGS1 (0.50) IP6K1IP6K3IP6K2ALDH1A1MEN1
SCHEMBL11373825 0.81 FABP3 (0.48) RXRARXRBRXRGALDH1A1PIN1
SCHEMBL11382101 0.79 ALDH1A1 (0.54) IP6K1IP6K3IP6K2RXRARXRB
SCHEMBL11378312 0.75 GPBAR1 (0.41) ALDH1A1KMONPC1RAB9AGPBAR1
SCHEMBL11384353 0.75 MEN1 (0.43) ALDH1A1SMN1; SMN2MEN1KMT2ANPC1
SCHEMBL11373634 0.74 TSHR (0.46) RXRARXRBRXRGSMN1; SMN2KMO
SCHEMBL13733019 0.73 GPBAR1 (0.64) IP6K1IP6K3IP6K2ALDH1A1SMN1; SMN2
SCHEMBL11379065 0.73 NPC1 (0.48) IP6K1IP6K3IP6K2ALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4243406-A REDUCING INJURIES TO CROP PLANTS WHEN USING AN ALPHA-HALOACETANILIDE AS A HERBICIDE MONSANTO COMPANY (US) 1981-01-06 US disclosed