SCHEMBL11375484

SCHEMBL11375484

Cc1noc(-c2cccc(C(F)(F)F)c2)c1C(=O)O

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IP6K1 Q92551 1/20 0.58
IP6K3 Q96PC2 1/20 0.58
IP6K2 Q9UHH9 1/20 0.58
BRD4 O60885 1/20 0.53
ALDH1A1 P00352 3/20 0.52
SMN1; SMN2 Q16637 1/20 0.52
XDH P47989 1/20 0.52
RXFP1 Q9HBX9 1/20 0.51
PIN1 Q13526 1/20 0.49
KMO O15229 2/20 0.46
LMNA P02545 2/20 0.46
GPBAR1 Q8TDU6 1/20 0.45
RXRA P19793 1/20 0.45
RXRB P28702 1/20 0.45
RXRG P48443 1/20 0.45
DHODH Q02127 1/20 0.44
NPC1 O15118 1/20 0.43
HTT P42858 1/20 0.43
RAB9A P51151 1/20 0.43
FLT1 P17948 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11375673 0.84 IP6K1 (0.55) IP6K1IP6K3IP6K2BRD4ALDH1A1
SCHEMBL8048080 0.83 TRPV1 (0.55) DHODHNPC1FLT1KDRKMT2A
SCHEMBL4339483 0.82 NR4A1 (0.44) IP6K1IP6K3IP6K2ALDH1A1SMN1; SMN2
SCHEMBL4032450 0.82 IP6K1 (0.58) IP6K1IP6K3IP6K2BRD4ALDH1A1
SCHEMBL928538 0.80 PTGS1 (0.54) IP6K1IP6K3IP6K2BRD4ALDH1A1
SCHEMBL3711076 0.80 PRNP (0.45) IP6K1IP6K3IP6K2BRD4ALDH1A1
SCHEMBL13733019 0.79 GPBAR1 (0.64) IP6K1IP6K3IP6K2BRD4ALDH1A1
Hydrochloric Acid SCHEMBL19119250 0.78 PTGS1 (0.53) IP6K1IP6K3IP6K2BRD4ALDH1A1
SCHEMBL4333981 0.77 ALDH1A1 (0.58) IP6K1IP6K3IP6K2BRD4ALDH1A1
SCHEMBL13508 0.77 PTGS1 (0.51) IP6K1IP6K3IP6K2BRD4ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4243406-A REDUCING INJURIES TO CROP PLANTS WHEN USING AN ALPHA-HALOACETANILIDE AS A HERBICIDE MONSANTO COMPANY (US) 1981-01-06 US disclosed