Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | XPO1 | O14980 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL181251 | 0.95 | — | — | |
| SCHEMBL11512900 | 0.92 | GSK3A (0.39) | GSK3AGSK3BMGLLKDM4ENPC1 | |
| Ether SCHEMBL10447389 | 0.81 | JUN (0.33) | GSK3AGSK3BMGLLKDM4ENPC1 | |
| Diphenylether SCHEMBL10446941 | 0.76 | MGLL (0.43) | MGLLKDM4ENPC1ALDH1A1MAPT | |
| SCHEMBL10951757 | 0.75 | — | — | |
| SCHEMBL11586874 | 0.70 | XPO1 (0.36) | GSK3AGSK3BMGLLXPO1 | |
| SCHEMBL4395914 | 0.70 | MGLL (0.33) | GSK3AGSK3BMGLLNPC1ALDH1A1 | |
| SCHEMBL2464170 | 0.69 | KDM4E (0.43) | KDM4ENPC1ALDH1A1MAPTRAB9A | |
| SCHEMBL8883684 | 0.67 | MGLL (0.46) | MGLLKDM4ENPC1ALDH1A1MAPT | |
| SCHEMBL8885500 | 0.67 | MGLL (0.41) | MGLLKDM4ENPC1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4271074-A | Silanes containing imide groups | CIBA-GEIGY CORPORATION (US) | 1981-06-02 | — | — | US | disclosed |