Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8315999 | 0.77 | THRB (0.42) | THRBLMNAEPHX1KMT2A | |
| SCHEMBL20324016 | 0.76 | — | — | |
| SCHEMBL853104 | 0.74 | THRB (0.40) | THRBLMNAEPHX1KMT2A | |
| SCHEMBL10639327 | 0.74 | THRB (0.35) | THRBLMNA | |
| SCHEMBL8506724 | 0.72 | AOC3 (0.32) | — | |
| SCHEMBL9508254 | 0.72 | THRB (0.38) | THRBLMNAEPHX1KMT2A | |
| SCHEMBL2263311 | 0.72 | KDM4E (0.41) | THRBLMNAEPHX1KMT2A | |
| SCHEMBL28000400 | 0.72 | THRB (0.38) | THRBLMNAEPHX1KMT2A | |
| SCHEMBL20327310 | 0.72 | — | — | |
| SCHEMBL10429287 | 0.71 | EPHX1 (0.36) | LMNAEPHX1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2807162-B1 | SUBSTITUTED PHENYLIMIDAZOPYRAZOLES AND USE THEREOF | Bayer Pharma AG (DE) | 2017-06-07 | — | — | EP | disclosed |
| EP-2807162-B1 | SUBSTITUTED PHENYLIMIDAZOPYRAZOLES AND USE THEREOF | Bayer Pharma AG (DE) | 2017-06-07 | — | — | EP | disclosed |
| CN-104411707-B | Substituted phenylimidazopyrazoles and their use | 拜耳药业股份公司 | 2017-03-01 | — | — | CN | disclosed |
| US-9394309-B2 | Substituted phenylimidazopyrazoles and their use | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2016-07-19 | — | — | US | disclosed |
| US-9394309-B2 | Substituted phenylimidazopyrazoles and their use | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2016-07-19 | — | — | US | disclosed |
| CN-104411707-A | Substituted phenylimidazopyrazoles and their use | Bayer Pharma AG | 2015-03-11 | — | — | CN | disclosed |
| US-20150005288-A1 | SUBSTITUTED PHENYLIMIDAZOPYRAZOLES AND USE THEREOF | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2015-01-01 | — | — | US | disclosed |
| US-20150005288-A1 | SUBSTITUTED PHENYLIMIDAZOPYRAZOLES AND USE THEREOF | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2015-01-01 | — | — | US | disclosed |
| EP-2807162-A1 | SUBSTITUTED PHENYLIMIDAZOPYRAZOLES AND USE THEREOF | Bayer Pharma Aktiengesellschaft (DE) | 2014-12-03 | — | — | EP | disclosed |
| EP-2421854-B1 | INHIBITORS OF BRUTON'S TYROSINE KINASE | HOFFMANN LA ROCHE (CH) | 2014-07-23 | — | — | EP | disclosed |
| US-5215982-A | Antibiotics | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-06-01 | — | — | US | disclosed |
| EP-0433854-A2 | 3-Aminopyrazolo heterocycles, their use for the determination of hydrogen peroxide, hydrogen peroxide forming systems, peroxidase, peroxidant active substances or electron rich aromatic compounds, corresponding determination process and agents | Roche Diagnostics GmbH (DE) | 1991-06-26 | — | — | EP | disclosed |
| EP-0433855-A2 | N- and O-substituted aminophenol derivatives, intermediates for their preparation, their use as hydrolase substrates, a corresponding assay and diagnostic agents | Roche Diagnostics GmbH (DE) | 1991-06-26 | — | — | EP | disclosed |
| EP-0427248-A2 | New cephem compounds and processes for preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-05-15 | — | — | EP | disclosed |
| EP-0353047-A2 | Use of imidazopyrazole derivatives as analgesics and anti-inflammatory agents | Sankyo Company Limited (JP) | 1990-01-31 | — | — | EP | disclosed |
| EP-0119741-B1 | METHOD OF PRODUCING MAGENTA IMAGES IN SILVER HALIDE COLOUR PHOTOGRAPHIC MATERIALS | FUJI PHOTO FILM CO., LTD. (JP) | 1988-05-11 | — | — | EP | disclosed |
| US-4500630-A | USING AN IMIDAZOLO(1,2-B)PYRAZOLE COUPLER | FUJI PHOTO FILM CO., LTD. (JP) | 1985-02-19 | — | — | US | disclosed |
| EP-0119741-A2 | Method of producing magenta images in silver halide colour photographic materials | FUJI PHOTO FILM CO., LTD. (JP) | 1984-09-26 | — | — | EP | disclosed |
| US-4322502-A | FOAMING AN UNSATURATED POLYESTER DISSOLVED IN UNSATURATED MONOMER,A PEROXIDE, ORGANOMETALLIC PROMOTER, AND A HYDRAZINE OR HYDROAZONE | UNIROYAL, INC. (US) | 1982-03-30 | — | — | US | disclosed |
| EP-0048050-A1 | Simultaneous expansion and cure of polyester resin composition | UNIROYAL, INC. (US) | 1982-03-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150005288-A1 | SUBSTITUTED PHENYLIMIDAZOPYRAZOLES AND USE THEREOF | VHL, FLT4, FLT1 | THRB 3306/4885LMNA 1988/4885EPHX1 2660/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.