Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8315999 | 0.77 | THRB (0.42) | THRBLMNAEPHX1ATMKMT2A | |
| SCHEMBL853104 | 0.74 | THRB (0.40) | THRBLMNAEPHX1KMT2A | |
| SCHEMBL1137579 | 0.72 | THRB (0.38) | THRBLMNAEPHX1KMT2A | |
| SCHEMBL2263311 | 0.72 | KDM4E (0.41) | THRBLMNAEPHX1KMT2A | |
| SCHEMBL28000400 | 0.72 | THRB (0.38) | THRBLMNAEPHX1KMT2A | |
| SCHEMBL8719720 | 0.71 | — | — | |
| SCHEMBL24307670 | 0.70 | EPHX1 (0.33) | THRBLMNAEPHX1 | |
| SCHEMBL10314187 | 0.70 | EPHX1 (0.46) | LMNAEPHX1ATMKMT2A | |
| SCHEMBL6556274 | 0.70 | EPHX1 (0.39) | THRBLMNAEPHX1ATM | |
| SCHEMBL10008936 | 0.70 | CYP2D6 (0.50) | THRBLMNAEPHX1ATMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230374034-A1 | NOVEL BICYCLIC COMPOUNDS | Prism BioLab Co., Ltd. (JP) | 2023-11-23 | — | — | US | disclosed |
| EP-0294099-B1 | COLOUR PHOTOTHERMOGRAPHIC ELEMENTS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1993-08-18 | — | — | EP | disclosed |
| US-4923792-A | BENZYLIDENE LEUCO COMPOUNDS AS COLOR-GENERATING REDUCING AGENTS, TOPCOAT OF POLYVINYL ALCOHOL | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1990-05-08 | — | — | US | disclosed |
| US-4883747-A | LIGHT SENSITIVE SILVER HALIDE, ORGANIC ACID SILVER SALT, LEUCO DYE | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1989-11-28 | — | — | US | disclosed |
| EP-0294099-A2 | Colour photothermographic elements | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1988-12-07 | — | — | EP | disclosed |
| EP-0053389-B1 | PROCESS FOR PREPARING CATIONIC SURFACE ACTIVE AGENTS | TOHO CHEMICAL INDUSTRY CO., LTD. (JP) | 1985-04-03 | — | — | EP | disclosed |
| US-4385184-A | QUATERNARYL AMMONIUM WITH HYDROXYPHENETHYL GROUP | TOHO CHEMICAL INDUSTRY CO., LTD. (JP) | 1983-05-24 | — | — | US | disclosed |
| EP-0053389-A1 | Process for preparing cationic surface active agents | TOHO CHEMICAL INDUSTRY CO., LTD. (JP) | 1982-06-09 | — | — | EP | disclosed |
| US-4129445-A | GERMANIUM,TIN OR CADMIUM SULFIDES AS NUCLEI FOR PHYSICAL DEVELOPMENT | FUJI PHOTO FILM CO., LTD. (JP) | 1978-12-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230374034-A1 | NOVEL BICYCLIC COMPOUNDS | NOTCH1, NOTCH2, HES1 | THRB 2023/4885LMNA 2319/4885EPHX1 2685/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.