Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBK1 | Q9UHD2 | 10/20 | 0.45 |
| ▸ | IKBKE | Q14164 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.40 |
| ▸ | TTR | P02766 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.40 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.40 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.39 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.39 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11368435 | 0.88 | TBK1 (0.52) | TBK1IKBKEKDM4ENPC1GAA | |
| Diethanolamine SCHEMBL11375023 | 0.82 | TBK1 (0.45) | TBK1IKBKEKDM4ENPC1GAA | |
| SCHEMBL11376611 | 0.80 | TBK1 (0.41) | TBK1IKBKEKDM4ENPC1GAA | |
| SCHEMBL19197533 | 0.77 | TBK1 (0.70) | TBK1IKBKEKDM4ENPC1GAA | |
| SCHEMBL11100149 | 0.75 | TBK1 (0.46) | TBK1IKBKEKDM4ENPC1GAA | |
| Diethanolamine SCHEMBL11372162 | 0.75 | TBK1 (0.37) | TBK1IKBKEKDM4ENPC1GAA | |
| SCHEMBL11481868 | 0.73 | TP53 (0.42) | TBK1NPC1RAB9APKMGPR35 | |
| SCHEMBL11375621 | 0.72 | CA1 (0.41) | TBK1IKBKEKDM4ENPC1GAA | |
| SCHEMBL11378177 | 0.72 | TBK1 (0.52) | TBK1IKBKEKDM4ENPC1RAB9A | |
| SCHEMBL11387767 | 0.69 | KDM1A (0.39) | NPC1RAB9APTPN1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4267332-A | ANTIALLERGENS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1981-05-12 | — | — | US | disclosed |