Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBK1 | Q9UHD2 | 9/20 | 0.52 |
| ▸ | IKBKE | Q14164 | 5/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TERT | O14746 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 3/20 | 0.31 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.31 |
| ▸ | CDK9 | P50750 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CASP3 | P42574 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11375621 | 0.84 | CA1 (0.41) | TBK1IKBKENPC1RAB9AMAPT | |
| SCHEMBL11368435 | 0.83 | TBK1 (0.52) | TBK1IKBKENPC1RAB9AMAPT | |
| SCHEMBL11387767 | 0.80 | KDM1A (0.39) | NPC1RAB9AMAPTTERTCA12 | |
| SCHEMBL11544885 | 0.76 | TBK1 (0.72) | TBK1IKBKENPC1RAB9APDE3A | |
| SCHEMBL11375110 | 0.76 | TBK1 (0.48) | TBK1IKBKENPC1RAB9AMAPT | |
| Diethanolamine SCHEMBL11375023 | 0.75 | TBK1 (0.45) | TBK1IKBKENPC1RAB9APDE3A | |
| SCHEMBL11376915 | 0.73 | MAOA (0.40) | MAPTSMN1; SMN2KDM4EMEN1KMT2A | |
| SCHEMBL11375841 | 0.72 | TBK1 (0.45) | TBK1IKBKENPC1RAB9AMAPT | |
| SCHEMBL19180138 | 0.71 | TBK1 (0.48) | TBK1IKBKENPC1RAB9APDE3A | |
| SCHEMBL19197533 | 0.69 | TBK1 (0.70) | TBK1IKBKENPC1RAB9APDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4267332-A | ANTIALLERGENS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1981-05-12 | — | — | US | disclosed |