Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 4/20 | 0.53 |
| ▸ | CA2 | P00918 | 4/20 | 0.53 |
| ▸ | KMO | O15229 | 2/20 | 0.53 |
| ▸ | CES2 | O00748 | 2/20 | 0.50 |
| ▸ | CES1 | P23141 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | PARP1 | P09874 | 1/20 | 0.47 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.47 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.47 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11375878 | 1.00 | GAA (0.61) | GAAALDH1A1KMT2ANPC1RAB9A | |
| SCHEMBL1373430 | 0.90 | ALDH1A1 (0.61) | GAAALDH1A1KMT2ANPC1RAB9A | |
| SCHEMBL11370111 | 0.80 | KMO (0.57) | ALDH1A1KMT2ACA1CA2KMO | |
| SCHEMBL11370109 | 0.80 | KMO (0.57) | ALDH1A1KMT2ACA1CA2KMO | |
| SCHEMBL2992502 | 0.80 | NPC1 (0.69) | GAAALDH1A1KMT2ANPC1RAB9A | |
| SCHEMBL2992505 | 0.80 | NPC1 (0.69) | GAAALDH1A1KMT2ANPC1RAB9A | |
| SCHEMBL2992510 | 0.80 | NPC1 (0.69) | GAAALDH1A1KMT2ANPC1RAB9A | |
| SCHEMBL6995755 | 0.79 | ALDH1A1 (0.65) | GAAALDH1A1KMT2ANPC1RAB9A | |
| SCHEMBL11374054 | 0.77 | KMO (0.58) | ALDH1A1KMOCES2CES1MAPT | |
| SCHEMBL8775309 | 0.77 | KMO (0.58) | ALDH1A1KMOCES2CES1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4271163-A | HYPOTENSIVE AGENTS | BASF AKTIENGESELLSCHAFT (DE) | 1981-06-02 | — | — | US | disclosed |