Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.34 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.34 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.34 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.34 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.32 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.32 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.32 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.32 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.32 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | FYN | P06241 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10956402 | 0.75 | SRD5A2 (0.41) | KDM4ESRD5A2SMN1; SMN2CES1ALDH1A1 | |
| SCHEMBL21508269 | 0.71 | CA12 (0.52) | CA12CA9CLK4DYRK1BTYRO3 | |
| SCHEMBL11155843 | 0.70 | KDM4E (0.37) | KDM4EALOX15TSHRSIRT1L3MBTL1 | |
| Bicarbonate SCHEMBL29928922 | 0.68 | CA12 (0.84) | CA12CA9CLK4DYRK1BTYRO3 | |
| Bicarbonate SCHEMBL21081705 | 0.68 | CA12 (0.84) | CA12CA9CLK4DYRK1BTYRO3 | |
| SCHEMBL3373516 | 0.68 | CA12 (0.53) | CA12CA9CLK4DYRK1BTYRO3 | |
| SCHEMBL3371700 | 0.67 | CA12 (0.56) | CA12CA9CLK4DYRK1BTYRO3 | |
| SCHEMBL28209349 | 0.65 | CA12 (0.62) | CA12CA9CLK4DYRK1BTYRO3 | |
| SCHEMBL12629638 | 0.65 | CA12 (0.48) | CA12CA9CLK4DYRK1BTYRO3 | |
| SCHEMBL14424495 | 0.63 | CA12 (0.47) | CA12CA9CLK4DYRK1BTYRO3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0030861-A2 | Isoquinoline acetic acids and pharmaceutical compositions thereof | PFIZER INC. (US) | 1981-06-24 | — | — | EP | disclosed |