Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | MAOA | P21397 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11821428 | 0.83 | MAOA (0.43) | SRD5A2ALDH1A1MAOACYP1A2NPC1 | |
| SCHEMBL8028626 | 0.77 | FGFR1 (0.44) | ALDH1A1MAOACYP1A2NPC1RAB9A | |
| SCHEMBL11375973 | 0.75 | CA12 (0.44) | SRD5A2ALDH1A1CES1KDM4ESMN1; SMN2 | |
| SCHEMBL15698079 | 0.75 | MAPT (0.44) | SRD5A2ALDH1A1NPC1RAB9ACYP2C19 | |
| SCHEMBL11155843 | 0.73 | KDM4E (0.37) | ALDH1A1NPC1RAB9ACYP2C19MEN1 | |
| SCHEMBL14884278 | 0.72 | MAOA (0.43) | SRD5A2ALDH1A1MAOACYP1A2NPC1 | |
| SCHEMBL24585720 | 0.71 | MIF (0.37) | ALDH1A1MAOACYP1A2NPC1RAB9A | |
| SCHEMBL15698031 | 0.71 | EYA3 (0.45) | SRD5A2ALDH1A1MAOACYP1A2ADRA2A | |
| SCHEMBL11661882 | 0.70 | SRD5A2 (0.40) | SRD5A2ALDH1A1MAOACYP1A2ADRA2A | |
| Fluorene SCHEMBL2131210 | 0.70 | SRD5A2 (0.60) | SRD5A2ALDH1A1MAOACYP1A2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0206241-A1 | Process for the preparation of cis-5-fluoro-2-methyl-1-(4-methylthiobenzylidene)-indene-3-acetic acid | ZAMBON S.p.A. (IT) | 1986-12-30 | — | — | EP | claimed |
| EP-0067508-B1 | AMIDINE DERIVATIVES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1985-10-30 | — | — | EP | claimed |