SCHEMBL11375992

SCHEMBL11375992

O=[N+]([O-])c1ccc(C=Cc2ccc(-c3ccc(C=Cc4ccc([N+](=O)[O-])cc4)cc3)cc2)cc1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 2/20 0.69
RAB9A P51151 3/20 0.68
MAPT P10636 3/20 0.68
NPC1 O15118 2/20 0.68
FBP1 P09467 1/20 0.67
PTGS2 P35354 6/20 0.63
PTGS1 P23219 2/20 0.63
CYP19A1 P11511 2/20 0.63
CA12 O43570 1/20 0.53
CA1 P00915 1/20 0.53
CA2 P00918 1/20 0.53
CA9 Q16790 1/20 0.53
CA14 Q9ULX7 1/20 0.53
MEN1 O00255 2/20 0.51
KMT2A Q03164 2/20 0.51
BCHE P06276 1/20 0.51
MAOB P27338 1/20 0.51
MAPK1 P28482 1/20 0.51
HTT P42858 1/20 0.51
SMN1; SMN2 Q16637 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11375977 1.00 APP (0.69) APPRAB9AMAPTNPC1FBP1
SCHEMBL9170804 0.93 APP (0.78) APPRAB9AMAPTNPC1FBP1
SCHEMBL14947048 0.93 APP (0.78) APPRAB9AMAPTNPC1FBP1
SCHEMBL9170800 0.93 APP (0.78) APPRAB9AMAPTNPC1FBP1
SCHEMBL458178 0.93 APP (0.78) APPRAB9AMAPTNPC1FBP1
SCHEMBL458177 0.93 APP (0.78) APPRAB9AMAPTNPC1FBP1
SCHEMBL28198 0.85 CA1 (0.67) APPMAPTCYP19A1CA12CA1
SCHEMBL6423919 0.85 CA1 (0.67) APPMAPTCYP19A1CA12CA1
SCHEMBL1405432 0.84 CYP19A1 (0.72) APPRAB9AMAPTNPC1FBP1
SCHEMBL1405433 0.84 CYP19A1 (0.72) APPRAB9AMAPTNPC1FBP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4260672-A Electrophotographic sensitive element having a photoconductive disazo pigment RICOH COMPANY, LTD. (JP) 1981-04-07 US disclosed