Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 2/20 | 0.78 |
| ▸ | RAB9A | P51151 | 3/20 | 0.76 |
| ▸ | MAPT | P10636 | 3/20 | 0.76 |
| ▸ | NPC1 | O15118 | 2/20 | 0.76 |
| ▸ | FBP1 | P09467 | 2/20 | 0.75 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.70 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.70 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.70 |
| ▸ | BCHE | P06276 | 1/20 | 0.56 |
| ▸ | MAOB | P27338 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | GALK1 | P51570 | 1/20 | 0.56 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL458178 | 1.00 | APP (0.78) | APPRAB9AMAPTNPC1FBP1 | |
| SCHEMBL9170804 | 1.00 | APP (0.78) | APPRAB9AMAPTNPC1FBP1 | |
| SCHEMBL9170800 | 1.00 | APP (0.78) | APPRAB9AMAPTNPC1FBP1 | |
| SCHEMBL14947048 | 1.00 | APP (0.78) | APPRAB9AMAPTNPC1FBP1 | |
| SCHEMBL11375992 | 0.93 | APP (0.69) | APPRAB9AMAPTNPC1FBP1 | |
| SCHEMBL11375977 | 0.93 | APP (0.69) | APPRAB9AMAPTNPC1FBP1 | |
| SCHEMBL5514209 | 0.91 | APP (0.67) | APPRAB9AMAPTNPC1FBP1 | |
| SCHEMBL1405433 | 0.91 | CYP19A1 (0.72) | APPRAB9AMAPTNPC1FBP1 | |
| SCHEMBL5514207 | 0.91 | APP (0.67) | APPRAB9AMAPTNPC1FBP1 | |
| SCHEMBL1405432 | 0.91 | CYP19A1 (0.72) | APPRAB9AMAPTNPC1FBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110086429-A1 | METHODS AND DEVICES FOR DETECTING OZONE AND CARBONYL-CONTAINING COMPOUNDS | SIGMA-ALDRICH CO. (US) | 2011-04-14 | — | — | US | claimed |
| EP-2232254-A1 | METHODS AND DEVICES FOR SIMULTANEOUSLY DETECTING OZONE AND CARBONYL- CONTAINING COMPOUNDS | Sigma-Aldrich Co. (US) | 2010-09-29 | — | — | EP | claimed |
| WO-2009086304-A1 | METHODS AND DEVICES FOR SIMULTANEOUSLY DETECTING OZONE AND CARBONYL- CONTAINING COMPOUNDS | SIGMA-ALDRICH CO. (US) | 2009-07-09 | — | — | WO | claimed |
| EP-4054715-A1 | BIVALENT LECA INHIBITORS TARGETING BIOFILM FORMATION OF PSEUDOMONAS AERUGINOSA | Helmholtz-Zentrum für Infektionsforschung GmbH (DE) | 2022-09-14 | — | — | EP | disclosed |
| US-11382991-B2 | Molecular probes for imaging of myelin | CASE WESTERN RESERVE UNIVERSITY (US) | 2022-07-12 | — | — | US | disclosed |
| WO-2021074275-A1 | EFFECTIVE PHOTOMODULATION OF LANTHANIDE (III) ION LUMINESCENCE IN THE VISIBLE OR NEAR-INFRARED RANGE | UNIVERSITE DE RENNES 1 (FR) | 2021-04-22 | — | — | WO | disclosed |
| CN-108003029-B | Method for preparing nitro compound by catalyzing nitric oxide with graphene | 南京偌赛医药科技有限公司 | 2020-11-13 | — | — | CN | disclosed |
| CN-110143897-A | The preparation method of 4,4`- diamino bibenzyl -2,2`- disulfonic acid | 浙江大学 | 2019-08-20 | — | — | CN | disclosed |
| US-20180339069-A1 | MOLECULAR PROBES FOR IMAGING OF MYELIN | CASE WESTERN RESERVE UNIVERSITY | 2018-11-29 | — | — | US | disclosed |
| EP-2910945-B1 | Molecular probes for imaging of myelin | UNIV CASE WESTERN RESERVE (US) | 2018-07-18 | — | — | EP | disclosed |
| US-9987379-B2 | Molecular probes for imaging of myelin | CASE WESTERN RESERVE UNIVERSITY (US) | 2018-06-05 | — | — | US | disclosed |
| EP-0206147-B1 | PROCESS FOR THE PREPARATION OF 4,4'-DINITRODIBENZYLS | BAYER AG (DE) | 1990-02-28 | — | — | EP | disclosed |
| US-4734532-A | HIGH SPEED OXIDATIVE DIMERIZATION OF 4-NITROTOLUENE | BAYER AKTIENGESELLSCHAFT (DE) | 1988-03-29 | — | — | US | disclosed |
| EP-0206147-A2 | Process for the preparation of 4,4'-dinitrodibenzyls | BAYER AG (DE) | 1986-12-30 | — | — | EP | disclosed |
| US-4533505-A | REACTION OF ETHYLENE IWITH ACID HALIDES IN THE PRESENCE OF A BASE AND A PALLADIUM CATALYST | CIBA-GEIGY CORPORATION (US) | 1985-08-06 | — | — | US | disclosed |
| EP-0062005-B1 | PROCESS FOR THE MANUFACTURE OF STYRENE AND/OR STILBENE DERIVATIVES | CIBA-GEIGY AG (CH) | 1985-06-26 | — | — | EP | disclosed |
| US-4504559-A | Disazo compounds and photoconductive composition as well as electrophotographic light sensitive element containing the same | FUJI PHOTO FILM CO., LTD. (JP) | 1985-03-12 | — | — | US | disclosed |
| US-4478757-A | Process for the manufacture of aromatic isocyanates | PRODUITS CHIMIQUES UGINE KUHLMANN (FR) | 1984-10-23 | — | — | US | disclosed |
| EP-0062005-A1 | Process for the manufacture of styrene and/or stilbene derivatives | CIBA-GEIGY AG (CH) | 1982-10-06 | — | — | EP | disclosed |
| US-4332739-A | Process for the manufacture of aromatic isocyanates | PRODUITS CHIMIQUES UGINE KUHLMANN (FR) | 1982-06-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180339069-A1 | MOLECULAR PROBES FOR IMAGING OF MYELIN | MAG, MYT1, PMP22 | APP 2179/4885RAB9A 2852/4885MAPT 676/4885 |
| US-11382991-B2 | Molecular probes for imaging of myelin | MAG, MYT1, PMP22 | APP 2179/4885RAB9A 2852/4885MAPT 676/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.