Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.55 |
| ▸ | MEN1 | O00255 | 7/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | EDNRB | P24530 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11639360 | 0.85 | MEN1 (0.53) | KMT2AMEN1LMNAKDM4EMAPT | |
| SCHEMBL11377719 | 0.85 | LMNA (0.64) | KMT2AMEN1LMNAKDM4EMAPT | |
| SCHEMBL11366169 | 0.80 | LMNA (0.51) | KMT2AMEN1LMNAKDM4EMAPT | |
| SCHEMBL11373523 | 0.80 | MEN1 (0.49) | KMT2AMEN1LMNAKDM4EMAPT | |
| SCHEMBL11445264 | 0.80 | KMT2A (0.45) | KMT2AMEN1LMNAKDM4EMAPT | |
| SCHEMBL11372364 | 0.77 | RXFP1 (0.62) | KMT2AMEN1LMNAKDM4EMAPT | |
| SCHEMBL11365043 | 0.76 | RXFP1 (0.53) | KMT2AMEN1LMNAKDM4EMAPT | |
| SCHEMBL10676306 | 0.75 | MEN1 (0.72) | KMT2AMEN1LMNAKDM4EMAPT | |
| SCHEMBL11365331 | 0.74 | RXFP1 (0.54) | KMT2AMEN1LMNAKDM4EMAPT | |
| SCHEMBL11035052 | 0.69 | ALDH1A1 (0.72) | KMT2AMEN1CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4281131-A | ANTIALLERGENS | SANDOZ, INC. (US) | 1981-07-28 | — | — | US | claimed |
| US-4187309-A | ANTIALLERGENS, ANTIHISTAMINES | SANDOZ, INC. (US) | 1980-02-05 | — | — | US | claimed |