Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.53 |
| ▸ | CDC25B | P30305 | 2/20 | 0.46 |
| ▸ | ELANE | P08246 | 1/20 | 0.44 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CDC25A | P30304 | 1/20 | 0.43 |
| ▸ | CDC25C | P30307 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1787314 | 0.83 | TSHR (0.69) | TSHRALDH1A1HSD17B10CDC25BKDM4E | |
| SCHEMBL17746738 | 0.82 | PIN1 (0.46) | TSHRALDH1A1HSD17B10CYP1A2PIN1 | |
| Benzene SCHEMBL27468891 | 0.81 | TSHR (0.65) | TSHRALDH1A1HSD17B10CDC25BKDM4E | |
| SCHEMBL1791574 | 0.81 | TSHR (0.65) | TSHRALDH1A1HSD17B10CDC25BKDM4E | |
| SCHEMBL9781664 | 0.80 | TSHR (0.69) | TSHRALDH1A1HSD17B10CDC25BKDM4E | |
| SCHEMBL1994129 | 0.79 | TSHR (0.67) | TSHRALDH1A1HSD17B10CDC25BKDM4E | |
| SCHEMBL27492791 | 0.78 | TSHR (0.61) | TSHRALDH1A1HSD17B10CDC25BKDM4E | |
| Diethyl Phthalate SCHEMBL29404255 | 0.77 | TSHR (1.00) | TSHRALDH1A1HSD17B10CDC25BKDM4E | |
| Diethyl Phthalate SCHEMBL22296 | 0.77 | TSHR (1.00) | TSHRALDH1A1HSD17B10CDC25BKDM4E | |
| Diethyl Phthalate SCHEMBL5306972 | 0.77 | TSHR (1.00) | TSHRALDH1A1HSD17B10CDC25BKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4273773-A | IN COMBINATION WITH A DIURETIC | AMERICAN HOME PRODUCTS CORPORATION (US) | 1981-06-16 | — | — | US | disclosed |