Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 4/20 | 0.42 |
| ▸ | MAOB | P27338 | 4/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.34 |
| ▸ | PTGIR | P43119 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MITF | O75030 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.31 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11383285 | 0.85 | MAOA (0.44) | MAOAMAOBSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL11382151 | 0.83 | MAOA (0.40) | MAOAMAOBSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL11392064 | 0.83 | MAOA (0.40) | MAOAMAOBSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL11382185 | 0.83 | MAOA (0.42) | MAOAMAOBSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL11380076 | 0.81 | MAOA (0.38) | MAOAMAOBSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL11391795 | 0.81 | ALDH1A1 (0.44) | MAOAMAOBSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL11383839 | 0.81 | MAOA (0.40) | MAOAMAOBLNPEPPTGIR | |
| SCHEMBL11385832 | 0.77 | MAOA (0.44) | MAOAMAOBPTGIRTP53MEN1 | |
| SCHEMBL11384181 | 0.77 | MAOA (0.44) | MAOAMAOBLNPEPPTGIRMEN1 | |
| SCHEMBL11389068 | 0.76 | CYP19A1 (0.41) | PTGIR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4285961-A | MICROBIOCIDES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1981-08-25 | — | — | US | disclosed |