Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | CTSD | P07339 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | MITF | O75030 | 1/20 | 0.47 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.47 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.47 |
| ▸ | CDC25A | P30304 | 1/20 | 0.46 |
| ▸ | CDC25B | P30305 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11375770 | 0.92 | MAPT (0.50) | TDP1ALDH1A1KDM4EGAAMAPT | |
| SCHEMBL1013691 | 0.89 | AKR1C3 (0.61) | TDP1ALDH1A1ATMGAAMAPT | |
| SCHEMBL11376779 | 0.84 | ALDH1A1 (0.46) | TDP1ALDH1A1ATML3MBTL1KDM4E | |
| Benzophenone SCHEMBL28461510 | 0.82 | ALDH1A1 (0.58) | TDP1ALDH1A1ATML3MBTL1GAA | |
| SCHEMBL30547074 | 0.82 | CTSD (0.63) | TDP1ALDH1A1KDM4EGAAMAPT | |
| SCHEMBL239328 | 0.82 | CTSD (0.63) | TDP1ALDH1A1KDM4EGAAMAPT | |
| SCHEMBL11373087 | 0.80 | PLA2G10 (0.50) | TDP1ALDH1A1ATMGAAMAPT | |
| Hydrazine SCHEMBL14300720 | 0.80 | CTSD (0.61) | TDP1ALDH1A1KDM4EGAAMAPT | |
| Hydroxyamine SCHEMBL14300671 | 0.80 | CTSD (0.61) | TDP1ALDH1A1KDM4EGAAMAPT | |
| Hydrochloric Acid SCHEMBL6692325 | 0.80 | CTSD (0.61) | TDP1ALDH1A1KDM4EGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4247474-A | POLYFUNCTIONAL ALKYLENE, CYCLOALKYLENE, OR ARYLENE DERIVATIVES; HYDROGEN CHLORIDE SALTS USED AS CURING AGENTS | HERCULES INCORPORATED (US) | 1981-01-27 | — | — | US | disclosed |