Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD1 | P21728 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
| ▸ | DRD5 | P21918 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
| ▸ | PDE2A | O00408 | 2/20 | 0.31 |
| ▸ | PTGDR | Q13258 | 2/20 | 0.31 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.31 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fumaric Acid SCHEMBL11157468 | 0.82 | SMN1; SMN2 (0.39) | KDM4EALDH1A1MAPTSMN1; SMN2NOTUM | |
| Fumaric Acid SCHEMBL11380659 | 0.82 | SMN1; SMN2 (0.39) | KDM4EALDH1A1MAPTSMN1; SMN2NOTUM | |
| SCHEMBL11155830 | 0.81 | KDM4E (0.38) | KDM4EALDH1A1MAPTSMN1; SMN2NOTUM | |
| SCHEMBL11160737 | 0.71 | DRD1 (0.43) | KDM4EMAPTSMN1; SMN2DRD2DRD1 | |
| SCHEMBL11168152 | 0.70 | GPR52 (0.41) | KDM4EALDH1A1MGLLDRD2DRD1 | |
| SCHEMBL11162257 | 0.68 | PTPN2 (0.38) | DRD2DRD1DRD4DRD5PTPN2 | |
| SCHEMBL11171087 | 0.68 | TDP1 (0.35) | SMN1; SMN2NOTUMKMT2ADRD2DRD1 | |
| SCHEMBL11215258 | 0.68 | DRD2 (0.42) | DRD2DRD1DRD4DRD5 | |
| SCHEMBL11168905 | 0.67 | PRNP (0.39) | KDM4EALDH1A1MAPTSMN1; SMN2KMT2A | |
| SCHEMBL11216603 | 0.66 | DRD1 (0.43) | KMT2ADRD2DRD1DRD4DRD5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4265890-A | ANTIPSYCHOTIC, ANTIEMETICS | SMITHKLINE CORPORATION (US) | 1981-05-05 | — | — | US | disclosed |