Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 6/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | ESR1 | P03372 | 6/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11385727 | 0.95 | MAPT (0.47) | L3MBTL1LMNAMAPTATMGAA | |
| SCHEMBL11385663 | 0.94 | ALDH1A1 (0.37) | L3MBTL1LMNAMAPTATMGAA | |
| SCHEMBL11377048 | 0.88 | MAPT (0.31) | L3MBTL1LMNAMAPTATMGAA | |
| SCHEMBL11391023 | 0.87 | TSHR (0.38) | L3MBTL1LMNAMAPTATMGAA | |
| SCHEMBL11385100 | 0.84 | POLB (0.33) | POLB | |
| SCHEMBL11386132 | 0.81 | TSHR (0.38) | LMNAMAPTTSHRHSD17B10CYP1A2 | |
| SCHEMBL11385921 | 0.79 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL11382314 | 0.78 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL11377845 | 0.78 | ALDH1A1 (0.32) | MAPTGAAALDH1A1 | |
| SCHEMBL11382418 | 0.75 | TSPO (0.32) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4268681-A | HERBICIDES, PLANT GROWTH REGULATORS, INSECTICIDES, MITICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1981-05-19 | — | — | US | disclosed |
| US-4185991-A | 4,5-Dichloro-imidazole derivatives and their use as herbicides | BAYER AKTIENGESELLSCHAFT (DE) | 1980-01-29 | — | — | US | disclosed |
| US-4178166-A | HERBICIDES, INSECTICIDES, PLANT GROWTH REGULATORS | BAYER AKTIENGESELLSCHAFT (DE) | 1979-12-11 | — | — | US | disclosed |