Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 15/20 | 0.68 |
| ▸ | ADRB1 | P08588 | 11/20 | 0.68 |
| ▸ | ADRB2 | P07550 | 10/20 | 0.68 |
| ▸ | DRD4 | P21917 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11261798 | 0.90 | ADRB3 (0.76) | ADRB3ADRB1ADRB2DRD4 | |
| SCHEMBL11372455 | 0.83 | GAA (0.49) | ADRB3ADRB1ADRB2 | |
| SCHEMBL11544863 | 0.83 | GAA (0.51) | ADRB3ADRB1ADRB2DRD4 | |
| SCHEMBL11543042 | 0.82 | HTR1A (0.62) | ADRB3ADRB1ADRB2DRD4 | |
| Hydrochloric Acid SCHEMBL11374081 | 0.82 | KMT2A (0.50) | ADRB3ADRB1ADRB2 | |
| SCHEMBL11541942 | 0.81 | GAA (0.51) | ADRB3ADRB1ADRB2DRD4 | |
| Hydrochloric Acid SCHEMBL11245484 | 0.80 | ADRB3 (0.67) | ADRB3ADRB1ADRB2DRD4 | |
| SCHEMBL11240124 | 0.80 | KMT2A (0.53) | DRD4 | |
| SCHEMBL2983464 | 0.80 | ADRB3 (0.74) | ADRB3ADRB1ADRB2 | |
| Hydrochloric Acid SCHEMBL11544827 | 0.79 | KMT2A (0.55) | DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4288442-A | Inhibiting adrenergic β-receptors with piperidinopropyl derivatives | BOEHRINGER MANNHEIM GMBH (DE) | 1981-09-08 | — | — | US | claimed |