Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | DRD4 | P21917 | 4/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 5/20 | 0.47 |
| ▸ | DRD2 | P14416 | 2/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.46 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11537535 | 0.90 | DRD4 (0.56) | MAPTDRD4L3MBTL1DRD2ADRB2 | |
| SCHEMBL11541942 | 0.84 | GAA (0.51) | GAATSHRKMT2AMEN1MAPT | |
| SCHEMBL11380697 | 0.83 | ADRB3 (0.68) | DRD4ADRB2ADRB1ADRB3 | |
| SCHEMBL11369754 | 0.82 | ADRB2 (0.50) | TSHRMAPTDRD4HTR1ADRD2 | |
| SCHEMBL11372455 | 0.81 | GAA (0.49) | GAATSHRKMT2AMEN1MAPT | |
| Hydrochloric Acid SCHEMBL11374081 | 0.80 | KMT2A (0.50) | GAATSHRKMT2AMEN1MAPT | |
| SCHEMBL11240124 | 0.80 | KMT2A (0.53) | GAATSHRKMT2AMEN1MAPT | |
| SCHEMBL11542048 | 0.80 | DRD4 (0.46) | GAAKMT2AMEN1DRD4L3MBTL1 | |
| Hydrochloric Acid SCHEMBL11544827 | 0.79 | KMT2A (0.55) | GAATSHRKMT2AMEN1MAPT | |
| SCHEMBL11539813 | 0.79 | DRD4 (0.49) | KMT2AMEN1DRD4L3MBTL1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4146630-A | HYPOTENSIVE AGENTS | BOEHRINGER MANNHEIM GMBH (DE) | 1979-03-27 | — | — | US | claimed |