Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 10/20 | 0.73 |
| ▸ | RAB9A | P51151 | 10/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.56 |
| ▸ | MAPT | P10636 | 6/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.56 |
| ▸ | MEN1 | O00255 | 5/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.56 |
| ▸ | PKM | P14618 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | C1R | P00736 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11380542 | 0.88 | NPC1 (0.73) | NPC1RAB9ASMN1; SMN2MAPTKMT2A | |
| SCHEMBL11377225 | 0.83 | NPC1 (0.66) | NPC1RAB9ASMN1; SMN2MAPTKMT2A | |
| SCHEMBL31430447 | 0.83 | NPC1 (0.60) | NPC1RAB9ASMN1; SMN2MAPTKMT2A | |
| SCHEMBL11384696 | 0.81 | NPC1 (0.58) | NPC1RAB9ASMN1; SMN2MAPTKMT2A | |
| SCHEMBL8062960 | 0.78 | RAB9A (0.54) | NPC1RAB9ASMN1; SMN2MAPTKMT2A | |
| SCHEMBL23175245 | 0.78 | NPC1 (0.77) | NPC1RAB9ASMN1; SMN2MAPTKMT2A | |
| SCHEMBL5803349 | 0.77 | NPC1 (0.69) | NPC1RAB9ASMN1; SMN2MAPTKMT2A | |
| SCHEMBL15022003 | 0.77 | RAB9A (0.78) | NPC1RAB9ASMN1; SMN2MAPTKMT2A | |
| SCHEMBL25245167 | 0.74 | NPC1 (0.54) | NPC1RAB9ASMN1; SMN2MAPTKMT2A | |
| SCHEMBL11388652 | 0.73 | NPC1 (0.73) | NPC1RAB9ASMN1; SMN2MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4275210-A | IMMUNOSUPPRESSIVE AGENTS, ANTIFERTILITY AGENTS, PROPHYLAXIS OF MAREK'S DISEASE IN CHICKENS AND HERBICIDES | ELI LILLY AND COMPANY (US) | 1981-06-23 | — | — | US | disclosed |
| US-4088770-A | ANTIFERTILITY, HERBICIDES | ELI LILLY AND COMPANY (US) | 1978-05-09 | — | — | US | disclosed |