SCHEMBL11380908

SCHEMBL11380908

CCC(F)(OCC1CO1)[Si](OC)(OC)OC

nearest known ligand 0.46

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.46
TSHR P16473 2/20 0.35
MAPK1 P28482 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.34
TDP1 Q9NUW8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5598840 0.77 ALDH1A1 (0.52) ALDH1A1TSHRMAPK1SMN1; SMN2TDP1
SCHEMBL28438416 0.75 ALDH1A1 (0.44) ALDH1A1TSHRMAPK1SMN1; SMN2TDP1
SCHEMBL5598359 0.74 ALDH1A1 (0.57) ALDH1A1TSHRMAPK1SMN1; SMN2TDP1
SCHEMBL5598281 0.71 ALDH1A1 (0.48) ALDH1A1TSHRMAPK1SMN1; SMN2TDP1
SCHEMBL28338833 0.69 ALDH1A1 (0.50) ALDH1A1TSHRMAPK1SMN1; SMN2
SCHEMBL10940288 0.69
SCHEMBL7170116 0.69 ALDH1A1 (0.60) ALDH1A1TSHRMAPK1SMN1; SMN2TDP1
SCHEMBL2305494 0.68
SCHEMBL5369450 0.68 ALDH1A1 (0.48) ALDH1A1TSHRMAPK1SMN1; SMN2TDP1
SCHEMBL11744628 0.67 ALDH1A1 (0.64) ALDH1A1TSHRMAPK1SMN1; SMN2TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0028137-A1 Dry planographic printing plate TORAY INDUSTRIES, INC. (JP) 1981-05-06 EP disclosed