SCHEMBL5369450

SCHEMBL5369450

CCC(C)(C[Si](OC)(OC)OC)OCC1CO1

nearest known ligand 0.48

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.48
TSHR P16473 3/20 0.38
MAPK1 P28482 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.33
TP53 P04637 2/20 0.32
MAPT P10636 2/20 0.32
HPGD P15428 2/20 0.32
MEN1 O00255 1/20 0.32
CYP1A2 P05177 1/20 0.32
KMT2A Q03164 1/20 0.32
PPARG P37231 1/20 0.32
HIF1A Q16665 1/20 0.32
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5360156 0.85 ALDH1A1 (0.47) ALDH1A1TSHRMAPK1SMN1; SMN2TP53
SCHEMBL5375611 0.83 ALDH1A1 (0.44) ALDH1A1TSHRMAPK1SMN1; SMN2TDP1
SCHEMBL17090716 0.82 ALDH1A1 (0.64) ALDH1A1TSHRMAPK1SMN1; SMN2TP53
SCHEMBL5369532 0.81 ALDH1A1 (0.53) ALDH1A1TSHRMAPK1SMN1; SMN2TP53
SCHEMBL5365508 0.80 SMN1; SMN2 (0.46) ALDH1A1TSHRMAPK1SMN1; SMN2TP53
SCHEMBL13991448 0.74 ALDH1A1 (0.53) ALDH1A1TSHRMAPK1SMN1; SMN2TP53
SCHEMBL5598840 0.72 ALDH1A1 (0.52) ALDH1A1TSHRMAPK1SMN1; SMN2TP53
SCHEMBL7957645 0.71 ALDH1A1 (0.50) ALDH1A1TSHRMAPK1SMN1; SMN2TP53
SCHEMBL11744628 0.70 ALDH1A1 (0.64) ALDH1A1TSHRMAPK1SMN1; SMN2TP53
SCHEMBL1700016 0.70 ALDH1A1 (0.64) ALDH1A1TSHRMAPK1SMN1; SMN2TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070251448-A1 Application method, applicator, optical member, and optical device SAKURADA KAZUAKI 2007-11-01 US disclosed
US-7250190-B2 Application method, applicator, optical member, and optical device SEIKO EPSON CORPORATION (JP) 2007-07-31 US disclosed
US-6773465-B1 Optical element ITOH OPTICAL INDUSTRIAL CO., LTD. (JP) 2004-08-10 US disclosed
US-20040142105-A1 Application method, applicator, optical member, and optical device SEIKO EPSON CORPORATION (JP) 2004-07-22 US disclosed
US-4294950-A POLYVALENT CARBOXYLIC ACID BONDED THERETO ITO OPTICAL INDUSTRIAL CO., LTD. (JP) 1981-10-13 US disclosed