Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | DPP4 | P27487 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | FAP | Q12884 | 1/20 | 0.40 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.40 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.40 |
| ▸ | ACACB | O00763 | 2/20 | 0.39 |
| ▸ | MLNR | O43193 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5743909 | 0.72 | ALDH1A1 (0.70) | MAPTALDH1A1LMNASMN1; SMN2KDM4E | |
| SCHEMBL5743912 | 0.72 | ALDH1A1 (0.70) | MAPTALDH1A1LMNASMN1; SMN2KDM4E | |
| SCHEMBL19059444 | 0.72 | SMN1; SMN2 (0.62) | MAPTALDH1A1HPGDSMN1; SMN2KDM4E | |
| SCHEMBL11369577 | 0.71 | HTT (0.50) | MAPTDPP4ALDH1A1HPGDLMNA | |
| SCHEMBL16825790 | 0.70 | KDM4E (0.45) | MAPTALDH1A1LMNASMN1; SMN2KDM4E | |
| SCHEMBL2628188 | 0.68 | POLB (0.59) | MAPTALDH1A1HPGDLMNASMN1; SMN2 | |
| SCHEMBL503308 | 0.68 | PLA2G4B (0.58) | MAPTALDH1A1HPGDSMN1; SMN2NPC1 | |
| SCHEMBL11376413 | 0.68 | PREP (0.59) | MAPTDPP4ALDH1A1HPGDLMNA | |
| SCHEMBL10725638 | 0.67 | PARP10 (0.53) | MAPTALDH1A1HPGDSMN1; SMN2KDM4E | |
| SCHEMBL11197112 | 0.67 | ALDH1A1 (0.41) | MAPTDPP4ALDH1A1SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4267174-A | AND PROCESS FOR ADMINISTERING | BOEHRINGER MANNHEIM, GMBH (DE) | 1981-05-12 | — | — | US | disclosed |