Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | DPP4 | P27487 | 3/20 | 0.47 |
| ▸ | FAP | Q12884 | 2/20 | 0.47 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.47 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.47 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11377543 | 0.83 | DPP4 (0.43) | EPHX2DPP4FAPDPP8DPP9 | |
| SCHEMBL11371154 | 0.83 | SIGMAR1 (0.43) | FAPALDH1A1SMN1; SMN2NPC1LMNA | |
| SCHEMBL11380434 | 0.81 | ALOX15 (0.54) | HTTDPP4FAPDPP8DPP9 | |
| SCHEMBL11377168 | 0.74 | DPP4 (0.37) | DPP4DPP8DPP9 | |
| SCHEMBL11376513 | 0.74 | KCNA1 (0.47) | LMNAHSD17B10 | |
| SCHEMBL11193892 | 0.73 | DPP4 (0.46) | HTTDPP4FAPDPP8DPP9 | |
| SCHEMBL11387722 | 0.73 | CHRNB2 (0.50) | HTTDPP4FAPDPP8DPP9 | |
| SCHEMBL11380278 | 0.73 | ATF4 (0.50) | ALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL11371767 | 0.72 | DPP4 (0.45) | DPP4ALDH1A1HPGDSMN1; SMN2LMNA | |
| SCHEMBL11382452 | 0.71 | MAPT (0.46) | DPP4FAPDPP8DPP9DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4282212-A | Immune-stimulating 1-(N-acylcarbamoyl)-2-cyanoaziridines | BOEHRINGER MANNHEIM GMBH (DE) | 1981-08-04 | — | — | US | disclosed |