Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.36 |
| ▸ | HTR3A | P46098 | 1/20 | 0.35 |
| ▸ | IRAK4 | Q9NWZ3 | 3/20 | 0.34 |
| ▸ | TYK2 | P29597 | 1/20 | 0.34 |
| ▸ | CRHR1 | P34998 | 4/20 | 0.34 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | MET | P08581 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1138599 | 0.90 | IRAK4 (0.40) | ACACBIRAK4 | |
| SCHEMBL1138383 | 0.90 | IRAK4 (0.40) | ACACBIRAK4 | |
| SCHEMBL1138382 | 0.90 | IRAK4 (0.40) | ACACBIRAK4 | |
| SCHEMBL18335068 | 0.85 | ACACB (0.37) | ACACBMAPK1HTR3AIRAK4 | |
| SCHEMBL4597097 | 0.83 | CYP11B1 (0.34) | ACACBIRAK4CRHR1CYP11B1CYP11B2 | |
| SCHEMBL14957612 | 0.81 | TLR2 (0.42) | MAPK1KDM1A | |
| SCHEMBL14685857 | 0.81 | TLR2 (0.42) | MAPK1KDM1A | |
| SCHEMBL13510930 | 0.81 | TLR2 (0.42) | MAPK1KDM1A | |
| SCHEMBL4487928 | 0.78 | CYP11B1 (0.32) | IRAK4CYP11B1CYP11B2 | |
| SCHEMBL16211916 | 0.77 | SLC6A9 (0.41) | IRAK4CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8071629-B2 | 2-pyridinylcycloalkylcarboxamide derivatives as fungicides | BAYER CROPSCIENCE AG (DE) | 2011-12-06 | — | — | US | disclosed |
| EP-1885712-B1 | NEW 2-PYRIDINYLCYCLOALKYLCARBOXAMIDE DERIVATIVES AS FUNGICIDES. | BAYER CROPSCIENCE AG (DE) | 2011-02-23 | — | — | EP | disclosed |
| US-20090099234-A1 | 2-pyridinylcycloalkylcarboxamide derivatives as fungicides | BAYER CROPSCIENCE AG (DE) | 2009-04-16 | — | — | US | disclosed |
| EP-1885712-A1 | NEW 2-PYRIDINYLCYCLOALKYLCARBOXAMIDE DERIVATIVES AS FUNGICIDES. | BAYER CROPSCIENCE SA (FR) | 2008-02-13 | — | — | EP | disclosed |
| WO-2006122955-A1 | NEW 2-PYRIDINYLCYCLOALKYLCARBOXAMIDE DERIVATIVES AS FUNGICIDES. | BAYER CROPSCIENCE SA (FR) | 2006-11-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090099234-A1 | 2-pyridinylcycloalkylcarboxamide derivatives as fungicides | CYP1A2, CYP4F2, CYP4F12 | ACACB 1242/4885MAPK1 3463/4885HTR3A 3565/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.