Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 8/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.37 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.37 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1138382 | 1.00 | IRAK4 (0.40) | IRAK4CHRM1LMNATSHRTAS1R3 | |
| SCHEMBL1138383 | 1.00 | IRAK4 (0.40) | IRAK4CHRM1LMNATSHRTAS1R3 | |
| SCHEMBL1138375 | 0.90 | ACACB (0.37) | IRAK4ACACB | |
| SCHEMBL4597097 | 0.79 | CYP11B1 (0.34) | IRAK4LMNASMN1; SMN2ACACB | |
| SCHEMBL16211916 | 0.78 | SLC6A9 (0.41) | IRAK4LMNATAS1R3TAS1R1TAS1R2 | |
| SCHEMBL16211914 | 0.78 | SLC6A9 (0.41) | IRAK4LMNATAS1R3TAS1R1TAS1R2 | |
| SCHEMBL16212162 | 0.78 | SLC6A9 (0.41) | IRAK4LMNATAS1R3TAS1R1TAS1R2 | |
| SCHEMBL14957288 | 0.77 | IRAK4 (0.43) | IRAK4CHRM1 | |
| SCHEMBL18335068 | 0.77 | ACACB (0.37) | IRAK4ACACB | |
| SCHEMBL2889710 | 0.76 | HCRTR1 (0.49) | IRAK4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8071629-B2 | 2-pyridinylcycloalkylcarboxamide derivatives as fungicides | BAYER CROPSCIENCE AG (DE) | 2011-12-06 | — | — | US | disclosed |
| EP-1885712-B1 | NEW 2-PYRIDINYLCYCLOALKYLCARBOXAMIDE DERIVATIVES AS FUNGICIDES. | BAYER CROPSCIENCE AG (DE) | 2011-02-23 | — | — | EP | disclosed |
| US-20090099234-A1 | 2-pyridinylcycloalkylcarboxamide derivatives as fungicides | BAYER CROPSCIENCE AG (DE) | 2009-04-16 | — | — | US | disclosed |
| EP-1885712-A1 | NEW 2-PYRIDINYLCYCLOALKYLCARBOXAMIDE DERIVATIVES AS FUNGICIDES. | BAYER CROPSCIENCE SA (FR) | 2008-02-13 | — | — | EP | disclosed |
| WO-2006122955-A1 | NEW 2-PYRIDINYLCYCLOALKYLCARBOXAMIDE DERIVATIVES AS FUNGICIDES. | BAYER CROPSCIENCE SA (FR) | 2006-11-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090099234-A1 | 2-pyridinylcycloalkylcarboxamide derivatives as fungicides | CYP1A2, CYP4F2, CYP4F12 | IRAK4 3455/4885CHRM1 900/4885LMNA 2965/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.