Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.61 |
| ▸ | UTRN | P46939 | 4/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | AHR | P35869 | 1/20 | 0.54 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | CETP | P11597 | 1/20 | 0.47 |
| ▸ | PTPN5 | P54829 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | XBP1 | P17861 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | CASP3 | P42574 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11276658 | 0.99 | HDAC6 (0.62) | HDAC6UTRNCYP1A2AHRMAOB | |
| SCHEMBL2247299 | 0.89 | UTRN (0.67) | HDAC6UTRNCYP1A2AHRMAOB | |
| SCHEMBL11384647 | 0.87 | HDAC6 (0.59) | HDAC6UTRNCYP1A2AHRMAOB | |
| SCHEMBL11234519 | 0.85 | RXFP1 (0.62) | HDAC6UTRNCYP1A2AHRMAOB | |
| SCHEMBL325885 | 0.85 | ESR1 (0.57) | HDAC6UTRNCYP1A2AHRKDM4E | |
| SCHEMBL14614442 | 0.80 | PTPN1 (0.52) | HDAC6UTRNCYP1A2AHRKDM4E | |
| SCHEMBL19664251 | 0.80 | UTRN (0.54) | HDAC6UTRNCYP1A2AHRMAOB | |
| SCHEMBL2242855 | 0.79 | PTPN2 (0.64) | HDAC6UTRNCYP1A2AHRKDM4E | |
| SCHEMBL13994723 | 0.79 | PTPN1 (0.57) | HDAC6UTRNCYP1A2AHRKDM4E | |
| SCHEMBL11238508 | 0.79 | RAB9A (0.66) | HDAC6UTRNCYP1A2AHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4250315-A | 2-(SUBSTITUTED AMINO-PHENYL), SULFONIC ACID SUBSTITUTED | HOFFMANN-LA ROCHE INC. (US) | 1981-02-10 | — | — | US | claimed |