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Sugi Predict / Compounds / SCHEMBL325885

SCHEMBL325885

SCHEMBL325885

O=S(=O)(O)c1ccc2oc(-c3ccc(-c4nc5cc(S(=O)(=O)O)ccc5o4)cc3)nc2c1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ESR1 P03372 1/20 0.57
▸ ESR2 Q92731 1/20 0.57
▸ PTPN1 P18031 12/20 0.56
▸ PTPN5 P54829 12/20 0.56
▸ PTPN2 P17706 11/20 0.56
▸ HSPD1 P10809 8/20 0.56
▸ HSPE1 P61604 8/20 0.56
▸ KDM4E B2RXH2 4/20 0.55
▸ GAA P10253 2/20 0.55
▸ KMT2A Q03164 2/20 0.55
▸ SMN1; SMN2 Q16637 2/20 0.55
▸ CACNA1B Q00975 1/20 0.55
▸ APBA1 Q02410 1/20 0.55
▸ ALDH1A1 P00352 3/20 0.54
▸ HDAC6 Q9UBN7 2/20 0.54
▸ MAPT P10636 2/20 0.54
▸ UTRN P46939 2/20 0.54
▸ XBP1 P17861 1/20 0.54
▸ CYP1A2 P05177 1/20 0.54
▸ AHR P35869 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14614442 0.94 PTPN1 (0.52) ESR1ESR2PTPN1PTPN5PTPN2
SCHEMBL2242855 0.93 PTPN2 (0.64) ESR1ESR2PTPN1PTPN5PTPN2
SCHEMBL11238508 0.93 RAB9A (0.66) ESR1ESR2PTPN1PTPN5PTPN2
SCHEMBL13994723 0.93 PTPN1 (0.57) PTPN1PTPN5PTPN2HSPD1HSPE1
SCHEMBL11234519 0.89 RXFP1 (0.62) ESR1ESR2PTPN1PTPN5PTPN2
SCHEMBL11232895 0.89 KDM4E (0.58) PTPN1PTPN5PTPN2HSPD1HSPE1
SCHEMBL15895562 0.87 ESR1 (0.57) ESR1ESR2PTPN1PTPN5PTPN2
SCHEMBL11242605 0.87 KDM4E (0.47) ESR1ESR2PTPN1PTPN5PTPN2
SCHEMBL11276658 0.86 HDAC6 (0.62) ESR1ESR2PTPN1PTPN5PTPN2
SCHEMBL11695143 0.86 PTPN1 (0.54) PTPN1PTPN5PTPN2HSPD1HSPE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0852134-B1 Use of a composition containing a ceramide and a sulphonic UV filter OREAL (FR) 2001-12-05 — — EP claimed
US-6190676-B1 FOR PROTECTING HAIR AGAINST ULTRAVIOLET RADIATION L'OREAL (FR) 2001-02-20 — — US claimed
US-6024944-A SUNSCCREEN AGENTS AND LIPIDS SOCIETE L'OREAL S.A. (FR) 2000-02-15 — — US claimed
EP-0728474-B1 Use of sulphonic acids as anti-acne agents in cosmetic or dermatological compositions OREAL (FR) 1997-11-19 — — EP claimed
EP-0671160-B1 Use of sulphonic acids as antiageing agents in cosmetic and/or dermatological compositions OREAL (FR) 1996-08-07 — — EP claimed
US-20210188883-A1 HYDROPHILIC SILANES DOW TORAY CO., LTD. (JP) 2021-06-24 — — US disclosed
US-10940099-B2 Pituitous silicone emulsions DOW SILICONES CORPORATION (US) 2021-03-09 — — US disclosed
EP-3233980-B1 METHOD OF PREPARING FUNCTIONALIZED PARTICLES DOW SILICONES CORP (US) 2020-02-19 — — EP disclosed
US-10358529-B2 Method of preparing functionalized particles DOW SILICONES CORPORATION (US) 2019-07-23 — — US disclosed
EP-3145486-B1 EMULSION OF CROSS-LINKED AMINOSILOXANE POLYMER DOW SILICONES CORP (US) 2019-02-20 — — EP disclosed
US-10172781-B2 Pituitous silicone fluid DOW SILICONES CORPORATION (US) 2019-01-08 — — US disclosed
US-10059806-B2 Aminosiloxane polymer and method of forming DOW SILICONES CORPORATION (US) 2018-08-28 — — US disclosed
US-20060167117-A1 Controlled release compositions DOW CORNING CORPORATION 2006-07-27 — — US disclosed
EP-1605902-A2 CONTROLLED RELEASE COMPOSITIONS Dow Corning Corporation (US) 2005-12-21 — — EP disclosed
WO-2005102261-A1 CONTROLLED RELEASE COMPOSITIONS DOW CORNING CORPORATION (US) 2005-11-03 — — WO disclosed
WO-2004084844-A2 CONTROLLED RELEASE COMPOSITIONS DOW CORNING CORPORATION (US) 2004-10-07 — — WO disclosed
US-6190676-B1 FOR PROTECTING HAIR AGAINST ULTRAVIOLET RADIATION L'OREAL (FR) 2001-02-20 — — US disclosed
US-6080415-A SEPARATE PACKAGES OF A FIRST COMPONENT OF A COSMETIC MEDIUM CONTAINING A PHOTOCHROMIC COLORING AGENT WHICH PRODUCES A COLOR IN THE PRESENCE OF ULTRAVIOLET RADIATION AND THE SECOND A SUNSCREENING AGENT; IMPROVED COLORANT EFFECT; PATTERNS L'OREAL (FR) 2000-06-27 — — US disclosed
US-6024944-A SUNSCCREEN AGENTS AND LIPIDS SOCIETE L'OREAL S.A. (FR) 2000-02-15 — — US disclosed
EP-0852134-A1 Use of a composition containing a ceramide and a sulphonic UV filter L'OREAL (FR) 1998-07-08 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10059806-B2 Aminosiloxane polymer and method of forming HRH3, H1-2, H1-0 ESR1 96/4885ESR2 153/4885PTPN1 3642/4885
US-10172781-B2 Pituitous silicone fluid GHRHR, SSTR3, SSTR1 ESR1 582/4885ESR2 654/4885PTPN1 3199/4885
US-20210188883-A1 HYDROPHILIC SILANES H1-4, H1-2, ITGA4 ESR1 3223/4885ESR2 2982/4885PTPN1 658/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.