Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 2/20 | 0.64 |
| ▸ | GABRD | O14764 | 2/20 | 0.64 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.64 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.64 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.64 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.64 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.64 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.64 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.64 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.64 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.64 |
| ▸ | GABRE | P78334 | 2/20 | 0.64 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.64 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.64 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.64 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.64 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11037113 | 0.84 | GABRP (0.73) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL30310279 | 0.79 | GABRP (0.79) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL11844102 | 0.79 | GABRP (0.67) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL11680657 | 0.79 | GABRP (0.79) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL11850703 | 0.78 | GABRP (0.65) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL10805397 | 0.78 | GABRP (0.77) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL5023108 | 0.78 | GABRP (1.00) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL18076411 | 0.78 | GABRP (0.72) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL11604854 | 0.77 | GABRP (0.57) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL11850706 | 0.77 | GABRP (0.75) | GABRPGABRDGABRA1GABRB1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4258187-A | REACTING 2-AMINO-BENZOPHENONE DERIVATIVES WITH A HYDROXYLAMINE SALT | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-03-24 | — | — | US | disclosed |
| EP-0000149-A1 | Process for preparing quinazolinone oxides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1979-01-10 | — | — | EP | disclosed |