SCHEMBL11680657

SCHEMBL11680657

CN(C(=O)CCl)c1ccc(Cl)cc1C(=O)c1ccccc1

nearest known ligand 0.79

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRP O00591 2/20 0.79
GABRD O14764 2/20 0.79
GABRA1 P14867 2/20 0.79
GABRB1 P18505 2/20 0.79
GABRG2 P18507 2/20 0.79
GABRB3 P28472 2/20 0.79
GABRA5 P31644 2/20 0.79
GABRA3 P34903 2/20 0.79
GABRA2 P47869 2/20 0.79
GABRB2 P47870 2/20 0.79
GABRA4 P48169 2/20 0.79
GABRE P78334 2/20 0.79
GABRA6 Q16445 2/20 0.79
GABRG1 Q8N1C3 2/20 0.79
GABRG3 Q99928 2/20 0.79
GABRQ Q9UN88 2/20 0.79
C5AR1 P21730 1/20 0.55
ALDH1A1 P00352 6/20 0.46
KDM4E B2RXH2 2/20 0.46
SMN1; SMN2 Q16637 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30310279 1.00 GABRP (0.79) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL11850706 0.90 GABRP (0.75) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL10805397 0.88 GABRP (0.77) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL5023108 0.88 GABRP (1.00) GABRPGABRDGABRA1GABRB1GABRG2
Bromide SCHEMBL11306196 0.87 GABRP (0.97) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL11037113 0.86 GABRP (0.73) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL18076411 0.85 GABRP (0.72) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL31541264 0.84 GABRP (0.56) GABRPGABRDGABRA1GABRB1GABRG2
Oxazafone SCHEMBL2108261 0.83 GABRP (0.69) GABRPGABRDGABRA1GABRB1GABRG2
Oxazafone SCHEMBL30090496 0.83 GABRP (0.69) GABRPGABRDGABRA1GABRB1GABRG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250033082-A1 METHOD AND COMPOSITION FOR REDUCING SOLVENT RELEASE FROM, AND REDUCING ODOR OF, AGROCHEMICAL FORMULATIONS ADAMA MAKHTESHIM LTD. (IL) 2025-01-30 US claimed
CN-118201991-A Methods and compositions for reducing solvent release from agrochemical formulations and reducing agrochemical formulation odor 安道麦马克西姆有限公司 2024-06-14 CN claimed
WO-2023073536-A1 METHOD AND COMPOSITION FOR REDUCING SOLVENT RELEASE FROM, AND REDUCING ODOR OF, AGROCHEMICAL FORMULATIONS ADAMA MAKHTESHIM LTD. (IL) 2023-05-04 WO claimed
CN-106397242-A Method for producing 2-(N-methyl chloride acetamido)-5-chlorobenzophenone 枣阳凤泽精细化工有限公司 2017-02-15 CN claimed
US-20250033082-A1 METHOD AND COMPOSITION FOR REDUCING SOLVENT RELEASE FROM, AND REDUCING ODOR OF, AGROCHEMICAL FORMULATIONS ADAMA MAKHTESHIM LTD. (IL) 2025-01-30 US disclosed
CN-118201991-A Methods and compositions for reducing solvent release from agrochemical formulations and reducing agrochemical formulation odor 安道麦马克西姆有限公司 2024-06-14 CN disclosed
WO-2023073536-A1 METHOD AND COMPOSITION FOR REDUCING SOLVENT RELEASE FROM, AND REDUCING ODOR OF, AGROCHEMICAL FORMULATIONS ADAMA MAKHTESHIM LTD. (IL) 2023-05-04 WO disclosed
US-20220162173-A1 COMPOSITIONS AND METHODS FOR REDUCING TACTILE DYSFUNCTION, ANXIETY, AND SOCIAL IMPAIRMENT PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2022-05-26 US disclosed
CN-106397242-A Method for producing 2-(N-methyl chloride acetamido)-5-chlorobenzophenone 枣阳凤泽精细化工有限公司 2017-02-15 CN disclosed
US-4049666-A THE 2-(N-(HALOALKYL OR HALOACYL)-N-(ACYLOXYALKYL OR CARBOBENZOXYALKYL)AMINOPHENYL) PYRIDYL KETONE INTERMEDIATES HOFFMAN-LA ROCHE INC. (US) 1977-09-20 US disclosed
US-4049667-A THE 2-(N-(HALO-CARBALKOXY-ALKYL OR ACYL)-N-(ACYLOXYALKYL OR CARBOBENZOXYALKYL)AMINOPHENYL) PYRIDYL KETONE INTERMEDIATES HOFFMANN-LA ROCHE INC. (US) 1977-09-20 US disclosed
US-4017532-A SEDATIVES, MUSCLE RELAXANTS, ANTICONVULSANTS HOFFMANN-LA ROCHE INC. (US) 1977-04-12 US disclosed
US-4017531-A SEDATIVE, MUSCLE RELAXANT, ANTICONVULSANT HOFFMANN-LA ROCHE INC. (US) 1977-04-12 US disclosed
US-4014916-A SEDATIVES, MUSCLE RELAXANTS AND ANTICONVULSANT AGENTS HOFFMANN-LA ROCHE INC. (US) 1977-03-29 US disclosed
US-3997591-A SEDATIVES, MUSCLE RELAXANT, ANTICONVULSANT HOFFMANN-LA ROCHE INC. (US) 1976-12-14 US disclosed
US-3996209-A Process for preparing benzodiazepines HOFFMANN-LA ROCHE INC. (US) 1976-12-07 US disclosed
US-3965151-A 2-(AMINO OR AMIDO)-BENZOPHENONES HOFFMANN-LA ROCHE INC. (US) 1976-06-22 US disclosed
US-3950383-A SEDATIVES, MUSCLE RELAXANTS, ANTIAGGRESSION CASSELLA FARBWERKE MAINKUR AKT (DT) 1976-04-13 US disclosed
US-3931314-A CNS SEDATIVES, MUSCLE RELAXANTS, ANTIAGGRESSION CASSELLA FARBWERKE MAINKUR AKTIENGESELLSCHAFT (DT) 1976-01-06 US disclosed
US-3931301-A SEDATIVE, ANTIAGGRESSION, MUSCLE RELAXANT CASSELLA FARBWERKE MAINKUR AKTIENGESELLSCHAFT (DT) 1976-01-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220162173-A1 COMPOSITIONS AND METHODS FOR REDUCING TACTILE DYSFUNCTION, ANXIETY, AND SOCIAL IMPAIRMENT GABBR1, GABBR2, PMP22 GABRP 17/4885GABRD 14/4885GABRA1 10/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.