Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GUSB | P08236 | 3/20 | 0.71 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.54 |
| ▸ | PDE5A | O76074 | 11/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | PDE1A | P54750 | 2/20 | 0.47 |
| ▸ | PDE1B | Q01064 | 2/20 | 0.47 |
| ▸ | PDE1C | Q14123 | 2/20 | 0.47 |
| ▸ | TTR | P02766 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11383679 | 0.91 | PDE5A (0.66) | GUSBMAPTPDE10APDE5AMEN1 | |
| SCHEMBL11374673 | 0.91 | GUSB (0.58) | GUSBNPC1TP53POLBMAPT | |
| SCHEMBL11553024 | 0.90 | GUSB (0.57) | GUSBNPC1TP53POLBMAPT | |
| SCHEMBL11380722 | 0.90 | PDE5A (0.59) | GUSBNPC1TP53POLBMAPT | |
| SCHEMBL11375259 | 0.89 | PDE5A (0.58) | GUSBMAPTPDE10APDE5AMEN1 | |
| SCHEMBL11554055 | 0.89 | GUSB (0.55) | GUSBNPC1TP53POLBMAPT | |
| SCHEMBL11378049 | 0.88 | GUSB (0.55) | GUSBNPC1TP53POLBMAPT | |
| SCHEMBL11382413 | 0.87 | GUSB (0.59) | GUSBPOLBMEN1KMT2A | |
| SCHEMBL11549471 | 0.86 | GUSB (0.53) | GUSBNPC1TP53POLBMAPT | |
| SCHEMBL11553636 | 0.86 | GUSB (0.52) | GUSBNPC1TP53POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4251531-A | ANTIALLERGENS | FARMITALIA CARLO ERBA S.P.A. (IT) | 1981-02-17 | — | — | US | claimed |
| US-4251531-A | ANTIALLERGENS | FARMITALIA CARLO ERBA S.P.A. (IT) | 1981-02-17 | — | — | US | disclosed |
| US-4251531-A | ANTIALLERGENS | FARMITALIA CARLO ERBA S.P.A. (IT) | 1981-02-17 | — | — | US | disclosed |