Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GUSB | P08236 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | PDE5A | O76074 | 14/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 9/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 9/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.44 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.44 |
| ▸ | PDE6C | P51160 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11550601 | 0.92 | GUSB (0.50) | GUSBNPC1TP53POLBMAPT | |
| SCHEMBL11551231 | 0.90 | MPL (0.50) | GUSBNPC1TP53POLBMAPT | |
| SCHEMBL11554058 | 0.87 | GUSB (0.51) | GUSBNPC1TP53POLBMAPT | |
| SCHEMBL11384695 | 0.86 | GUSB (0.71) | GUSBNPC1TP53POLBMAPT | |
| SCHEMBL11552844 | 0.85 | GUSB (0.49) | GUSBNPC1TP53POLBMAPT | |
| SCHEMBL11556064 | 0.85 | GUSB (0.49) | GUSBNPC1TP53POLBMAPT | |
| SCHEMBL11550603 | 0.82 | GUSB (0.47) | GUSBNPC1TP53POLBMAPT | |
| SCHEMBL11556538 | 0.82 | TSHR (0.47) | GUSBNPC1TP53POLBMAPT | |
| SCHEMBL11553024 | 0.81 | GUSB (0.57) | GUSBNPC1TP53POLBMAPT | |
| SCHEMBL11550624 | 0.80 | KDM4E (0.54) | GUSBNPC1MAPTL3MBTL1PDE5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4159330-A | ANTIALLERGENS | CARLO ERBA S.P.A. (IT) | 1979-06-26 | — | — | US | claimed |
| US-4159330-A | ANTIALLERGENS | CARLO ERBA S.P.A. (IT) | 1979-06-26 | — | — | US | disclosed |