Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 17/20 | 0.59 |
| ▸ | GUSB | P08236 | 1/20 | 0.57 |
| ▸ | PDE4A | P27815 | 4/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.47 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | PDE2A | O00408 | 1/20 | 0.47 |
| ▸ | PDE6D | O43924 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | PDE9A | O76083 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | PDE6A | P16499 | 1/20 | 0.47 |
| ▸ | PDE6G | P18545 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11375259 | 0.97 | PDE5A (0.58) | PDE5AGUSBPDE4APDE4BPDE4C | |
| SCHEMBL11383679 | 0.95 | PDE5A (0.66) | PDE5AGUSBPDE4APDE4BPDE4C | |
| SCHEMBL11384695 | 0.90 | GUSB (0.71) | PDE5AGUSBMAPTMEN1PDE1A | |
| SCHEMBL11384809 | 0.90 | GUSB (0.56) | PDE5AGUSBPDE4APDE4BPDE4C | |
| SCHEMBL11374673 | 0.90 | GUSB (0.58) | PDE5AGUSBPDE4APDE4BPDE4C | |
| SCHEMBL11376529 | 0.89 | PDE5A (0.48) | PDE5AGUSBPDE4APDE4BPDE4C | |
| SCHEMBL11381831 | 0.88 | PDE5A (0.46) | PDE5AGUSBMAPTKDM4EALDH1A1 | |
| SCHEMBL11375179 | 0.88 | PDE5A (0.45) | PDE5AGUSBMAPTKDM4EALDH1A1 | |
| SCHEMBL11551096 | 0.87 | GUSB (0.48) | PDE5AGUSBPDE4APDE4BPDE4C | |
| SCHEMBL11549969 | 0.87 | GUSB (0.49) | PDE5AGUSBPDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4251531-A | ANTIALLERGENS | FARMITALIA CARLO ERBA S.P.A. (IT) | 1981-02-17 | — | — | US | claimed |
| US-4251531-A | ANTIALLERGENS | FARMITALIA CARLO ERBA S.P.A. (IT) | 1981-02-17 | — | — | US | disclosed |