Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 11/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | ATM | Q13315 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4901912 | 0.93 | TSHR (0.74) | TSHRHPGDATMALDH1A1CYP3A4 | |
| SCHEMBL9515977 | 0.91 | TSHR (0.61) | TSHRHPGDATMALDH1A1CYP3A4 | |
| SCHEMBL2708767 | 0.89 | TSHR (0.67) | TSHRHPGDATMALDH1A1CYP3A4 | |
| SCHEMBL10797039 | 0.89 | TSHR (0.71) | TSHRHPGDATMALDH1A1CYP3A4 | |
| SCHEMBL1823127 | 0.89 | TSHR (0.71) | TSHRHPGDATMALDH1A1CYP3A4 | |
| SCHEMBL30200835 | 0.89 | TSHR (0.71) | TSHRHPGDATMALDH1A1CYP3A4 | |
| SCHEMBL1448030 | 0.88 | TSHR (0.70) | TSHRHPGDATMALDH1A1CYP3A4 | |
| SCHEMBL10773417 | 0.88 | TSHR (0.66) | TSHRHPGDATMALDH1A1CYP3A4 | |
| SCHEMBL9227581 | 0.88 | TSHR (0.66) | TSHRHPGDATMALDH1A1CYP3A4 | |
| SCHEMBL6849095 | 0.87 | TSHR (0.69) | TSHRHPGDATMALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4296006-A | ACRYLIC POLYMER, FOR ROAD MARKINGS | DEGUSSA AKTIENGESELLSCHAFT (DE) | 1981-10-20 | — | — | US | disclosed |