Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.41 |
| ▸ | PRCP | P42785 | 8/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | L3MBTL4 | Q8NA19 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11386167 | 1.00 | TMEM97 (0.41) | TMEM97PRCPOPRD1KCNH2L3MBTL4 | |
| Hydrochloric Acid SCHEMBL11322106 | 0.99 | PRCP (0.40) | TMEM97PRCPOPRD1KCNH2L3MBTL4 | |
| SCHEMBL11326244 | 0.91 | OPRD1 (0.46) | TMEM97PRCPOPRD1KCNH2 | |
| SCHEMBL11326247 | 0.91 | OPRD1 (0.46) | TMEM97PRCPOPRD1KCNH2 | |
| Hydrochloric Acid SCHEMBL11330675 | 0.90 | OPRD1 (0.46) | TMEM97PRCPOPRD1KCNH2 | |
| Hydrochloric Acid SCHEMBL11331866 | 0.90 | OPRD1 (0.46) | TMEM97PRCPOPRD1KCNH2 | |
| SCHEMBL11318496 | 0.89 | PRCP (0.42) | TMEM97PRCPOPRD1KCNH2 | |
| SCHEMBL11318500 | 0.89 | PRCP (0.42) | TMEM97PRCPOPRD1KCNH2 | |
| SCHEMBL11329553 | 0.82 | HTR2A (0.43) | TMEM97PRCPOPRD1KCNH2 | |
| SCHEMBL11335083 | 0.82 | HTR2A (0.43) | TMEM97PRCPOPRD1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4263317-A | Spiro[cyclohexane-1,1'(3'H)-isobenzofuran]s | HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) | 1981-04-21 | — | — | US | claimed |