Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 2/20 | 0.36 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.33 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.33 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.33 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.32 |
| ▸ | ALB | P02768 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.32 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.32 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.32 |
| ▸ | EP300 | Q09472 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8910525 | 0.80 | FGFR1 (0.36) | FGFR1SLC22A6PDE3APDE4DSLC29A1 | |
| SCHEMBL14125693 | 0.79 | FGFR1 (0.35) | FGFR1SLC22A6PDE3APDE4DSLC29A1 | |
| SCHEMBL10634248 | 0.78 | FGFR1 (0.37) | FGFR1SLC22A6PDE3APDE4DSLC29A1 | |
| SCHEMBL15798503 | 0.77 | PDE3A (0.33) | FGFR1SLC22A6PDE3APDE4DSLC29A1 | |
| SCHEMBL16653681 | 0.75 | PDE3A (0.33) | FGFR1SLC22A6PDE3APDE4DSLC29A1 | |
| SCHEMBL11385010 | 0.74 | ALB (0.34) | ALBEP300 | |
| SCHEMBL8140845 | 0.74 | LMNA (0.39) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL8007933 | 0.72 | FGFR1 (0.35) | FGFR1SLC22A6PDE3APDE4DSLC29A1 | |
| SCHEMBL5586430 | 0.71 | KDM4E (0.32) | MAPT | |
| SCHEMBL1065338 | 0.71 | FGFR1 (0.35) | FGFR1SLC22A6PDE3APDE4DSLC29A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4246411-A | ANTICARCINOGENIC AGENTS | PCR INCORPORATED (US) | 1981-01-20 | — | — | US | disclosed |
| US-4029661-A | OR ALCOHOL SOLVENTSFLUORINATION | PCR, INC. (US) | 1977-06-14 | — | — | US | disclosed |