Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.35 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.35 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.35 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.33 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.33 |
| ▸ | ALB | P02768 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.33 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.33 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL176469 | 0.86 | FGFR1 (0.34) | FGFR1LMNATHRBMTORMDM2 | |
| SCHEMBL7743090 | 0.74 | POLG (0.40) | FGFR1SLC22A6 | |
| SCHEMBL1065338 | 0.74 | FGFR1 (0.35) | FGFR1LMNATHRBMTORMDM2 | |
| SCHEMBL27503114 | 0.74 | FGFR1 (0.35) | FGFR1LMNATHRBMTORMDM2 | |
| SCHEMBL8910525 | 0.74 | FGFR1 (0.36) | FGFR1LMNATHRBMTORMDM2 | |
| SCHEMBL440453 | 0.73 | PDE3A (0.35) | FGFR1LMNATHRBMTORMDM2 | |
| SCHEMBL1629582 | 0.72 | FGFR1 (0.44) | FGFR1LMNATHRBMTORMDM2 | |
| SCHEMBL14125693 | 0.72 | FGFR1 (0.35) | FGFR1LMNATHRBMTORMDM2 | |
| SCHEMBL7743127 | 0.72 | FGFR1 (0.35) | FGFR1LMNATHRBMTORMDM2 | |
| SCHEMBL11387331 | 0.72 | FGFR1 (0.36) | FGFR1LMNATHRBMTORMDM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000023801-A9 | SYSTEM FOR APPLYING CONTROLLED PRESSURE PROFILES TO BIOLOGICAL SAMPLES AND METHODS RELATING THERETO | ADVANCED RES & TECH INST (US) | 2000-09-28 | — | — | WO | disclosed |
| WO-2000023801-A1 | SYSTEM FOR APPLYING CONTROLLED PRESSURE PROFILES TO BIOLOGICAL SAMPLES AND METHODS RELATING THERETO | ADVANCED RESEARCH AND TECHNOLOGY INSTITUTE, INC. (US) | 2000-04-27 | — | — | WO | disclosed |