Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ECE2 | P0DPD6 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | CASP3 | P42574 | 2/20 | 0.49 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.49 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.49 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.49 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.43 |
| ▸ | CDK4 | P11802 | 1/20 | 0.43 |
| ▸ | CCND1 | P24385 | 1/20 | 0.43 |
| ▸ | JUN | P05412 | 1/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11387706 | 1.00 | ECE2 (0.50) | ECE2MEN1NPC1KMT2ALMNA | |
| SCHEMBL108389 | 0.76 | TRPA1 (0.76) | ECE2MEN1NPC1KMT2ALMNA | |
| SCHEMBL717976 | 0.76 | TRPA1 (0.76) | ECE2MEN1NPC1KMT2ALMNA | |
| SCHEMBL5038547 | 0.73 | MEN1 (0.54) | MEN1NPC1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL6982031 | 0.73 | MEN1 (0.54) | MEN1NPC1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL708945 | 0.72 | NPC1 (0.64) | ECE2MEN1NPC1KMT2ATRPA1 | |
| SCHEMBL708946 | 0.72 | NPC1 (0.64) | ECE2MEN1NPC1KMT2ATRPA1 | |
| SCHEMBL11388911 | 0.71 | ECE2 (0.46) | ECE2MEN1NPC1KMT2ALMNA | |
| SCHEMBL11388913 | 0.71 | ECE2 (0.46) | ECE2MEN1NPC1KMT2ALMNA | |
| Hydrochloric Acid SCHEMBL16915472 | 0.70 | NPC1 (0.61) | ECE2MEN1NPC1KMT2ATRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0034754-A1 | 2-((3-amino-2-hydroxy-propoxy)-styryl) isoxazoles, process for their preparation and pharmaceutical compositions containing them | BASF Aktiengesellschaft (DE) | 1981-09-02 | — | — | EP | disclosed |
| EP-0034754-A1 | 2-((3-amino-2-hydroxy-propoxy)-styryl) isoxazoles, process for their preparation and pharmaceutical compositions containing them | BASF Aktiengesellschaft (DE) | 1981-09-02 | — | — | EP | disclosed |
| US-4251539-A | HYPOTENSIVE AGENTS, ANTIARRHYTHMIA AGENTS | BASF AKTIENGESELLSCHAFT (DE) | 1981-02-17 | — | — | US | disclosed |
| EP-0005186-A1 | 3-Alkyl-5-(2-hydroxystyryl)-isoxazoles and process for their preparation | BASF Aktiengesellschaft (DE) | 1979-11-14 | — | — | EP | disclosed |
| EP-0005192-A1 | Alkylaminopropanol derivatives of 3-alkyl-5-(2-hydroxystyryl)-isoxazoles, processes for their preparation and therapeutical compositions containing them | BASF Aktiengesellschaft (DE) | 1979-11-14 | — | — | EP | disclosed |