Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | HPGD | P15428 | 4/20 | 0.48 |
| ▸ | GRM4 | Q14833 | 5/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | GRM5 | P41594 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6982031 | 1.00 | MEN1 (0.54) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL1176652 | 0.81 | MEN1 (0.35) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL29089469 | 0.80 | NFE2L2 (0.45) | KDM4EHPGDGRM4RAB9ANPC1 | |
| SCHEMBL31280552 | 0.80 | RAB9A (0.44) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL29089460 | 0.76 | MAPT (0.59) | KDM4EALDH1A1HPGDRAB9ANPC1 | |
| SCHEMBL11387702 | 0.73 | ECE2 (0.50) | MEN1KMT2ARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL2465326 | 0.73 | — | — | |
| SCHEMBL710247 | 0.71 | MEN1 (0.54) | MEN1KMT2AALDH1A1GRM4RAB9A | |
| (Z)-1,2-Diphenylethene SCHEMBL443 | 0.71 | MAOB (0.73) | MEN1KMT2AALDH1A1HDAC6LMNA | |
| (Z)-1,2-Diphenylethene SCHEMBL9134305 | 0.71 | MAOB (0.73) | MEN1KMT2AALDH1A1HDAC6LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115536649-B | Polysubstituted pyrazoline compound and synthesis method thereof | 成都中医药大学 | 2024-12-20 | — | — | CN | disclosed |
| CN-115536649-A | Polysubstituted pyrazoline compound and synthesis method thereof | 四川普康药业有限公司 | 2022-12-30 | — | — | CN | disclosed |
| US-9593071-B2 | Process for the preparation of gamma amino acids and intermediates used in said process | ROYAL COLLEGE OF SURGEONS IN IRELAND (IE) | 2017-03-14 | — | — | US | disclosed |
| CN-104220433-A | Process for preparing gamma amino acids and intermediates useful in said process | ROYAL COLLEGE OF SURGEONS IE | 2014-12-17 | — | — | CN | disclosed |
| US-20140336412-A1 | PROCESS FOR THE PREPARATION OF GAMMA AMINO ACIDS AND INTERMEDIATES USED IN SAID PROCESS | ROYAL COLLEGE OF SURGEONS IN IRELAND (IE) | 2014-11-13 | — | — | US | disclosed |
| EP-2782911-A1 | PROCESS FOR THE PREPARATION OF GAMMA AMINO ACIDS AND INTERMEDIATES USED IN SAID PROCESS | Royal College of Surgeons in Ireland (IE) | 2014-10-01 | — | — | EP | disclosed |
| WO-2013076225-A1 | PROCESS FOR THE PREPARATION OF GAMMA AMINO ACIDS AND INTERMEDIATES USED IN SAID PROCESS | ROYAL COLLEGE OF SURGEONS IN IRELAND (IE) | 2013-05-30 | — | — | WO | disclosed |
| US-7319150-B2 | Method for preparing styryl pyrazole, isoxazole and isothiazole derivatives | LABORATOIRES MAYOLY SPINDLER (FR) | 2008-01-15 | — | — | US | disclosed |
| US-7319150-B2 | Method for preparing styryl pyrazole, isoxazole and isothiazole derivatives | LABORATOIRES MAYOLY SPINDLER (FR) | 2008-01-15 | — | — | US | disclosed |
| US-20060135580-A1 | Novel method for preparing styryl pyrazole, isoxazole and isothiazole derivatives | UNIVERSITE MONTPELLIER 2 (FR) | 2006-06-22 | — | — | US | disclosed |
| EP-0749429-B1 | 3,5-DISUBSTITUTED AND 3,5,6-TRISUBSTITUTED 2-ISOXAZOLINES AND ISOXAZOLES, PROCESS FOR PREPARING THE SAME AND THEIR USE AS MEDICAMENTS | HOECHST AG (DE) | 1999-06-30 | — | — | EP | disclosed |
| EP-0904272-A1 | DIHYDROBENZOFURAN AND RELATED COMPOUNDS USEFUL AS ANTI-INFLAMMATORY AGENTS | THE PROCTER & GAMBLE COMPANY (US) | 1999-03-31 | — | — | EP | disclosed |
| CN-1210534-A | Dihydrobenzofuran and related compounds useful as anti-inflammatory agents | PROCTER & GAMBLE (US) | 1999-03-10 | — | — | CN | disclosed |
| US-5686471-A | Dihydrobenzofuran and related compounds useful as anti-inflammatory agents | THE PROCTER & GAMBLE COMPANY (US) | 1997-11-11 | — | — | US | disclosed |
| WO-1997028155-A1 | DIHYDROBENZOFURAN AND RELATED COMPOUNDS USEFUL AS ANTI-INFLAMMATORY AGENTS | THE PROCTER & GAMBLE COMPANY (US) | 1997-08-07 | — | — | WO | disclosed |
| US-5208251-A | Compounds for antiinflammatory agents, antiallergens, antiarthritic, antiulcer agents | WARNER-LAMBERT COMPANY (US) | 1993-05-04 | — | — | US | disclosed |
| EP-0245825-B1 | STYRYL PYRAZOLES, ISOXAZOLES AND ANALOGS THEREOF HAVING ACTIVITY AS 5-LIPOXY-GENASE INHIBITORS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | WARNER-LAMBERT COMPANY (US) | 1991-03-13 | — | — | EP | disclosed |
| US-4924002-A | REACTION WITH MOLYBDENUM CARBONYL AND HYDRAZINE | WARNER-LAMBERT COMPANY (US) | 1990-05-08 | — | — | US | disclosed |
| US-4877881-A | SUNSCREEN | WARNER-LAMBERT COMPANY (US) | 1989-10-31 | — | — | US | disclosed |
| EP-0245825-A1 | Styryl pyrazoles, isoxazoles and analogs thereof having activity as 5-lipoxy-genase inhibitors and pharmaceutical compositions containing them | WARNER-LAMBERT COMPANY (US) | 1987-11-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060135580-A1 | Novel method for preparing styryl pyrazole, isoxazole and isothiazole derivatives | ADH5, ADH1A, STK35 | MEN1 4475/4885KMT2A 3612/4885KDM4E 4089/4885 |
| US-20140336412-A1 | PROCESS FOR THE PREPARATION OF GAMMA AMINO ACIDS AND INTERMEDIATES USED IN SAID PROCESS | GLRB, GABRP, GABRG1 | MEN1 3346/4885KMT2A 3770/4885KDM4E 2847/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.