Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 9/20 | 0.40 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.38 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | PRNP | P04156 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pirquinozol SCHEMBL635679 | 0.83 | ADORA3 (0.59) | ALDH1A1ADORA3 | |
| SCHEMBL11406627 | 0.80 | ADORA3 (0.47) | ALDH1A1ADORA3 | |
| SCHEMBL11392211 | 0.76 | ADORA3 (0.54) | ALDH1A1ADORA3PDE7APDE7BKMT2A | |
| SCHEMBL11254079 | 0.72 | ADORA3 (0.56) | ALDH1A1ADORA3HPGD | |
| SCHEMBL11391453 | 0.72 | ADORA3 (0.77) | ALDH1A1ADORA3KMT2AKDM4EMEN1 | |
| SCHEMBL31461654 | 0.71 | SMN1; SMN2 (0.43) | ALDH1A1ADORA3KMT2AKDM4EMEN1 | |
| SCHEMBL11395024 | 0.69 | PDE7A (0.44) | ALDH1A1ADORA3PDE7APDE7BKMT2A | |
| SCHEMBL16370935 | 0.69 | PDE7A (0.44) | ALDH1A1PDE7APDE7BKMT2AKDM4E | |
| SCHEMBL11288740 | 0.69 | ADORA3 (0.56) | ADORA3 | |
| SCHEMBL11250103 | 0.69 | ADORA3 (0.58) | ALDH1A1ADORA3KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4282226-A | Thioxopyrazolo[1,5-c]quinazoline derivatives, anti-allergic compositions and methods for treating allergic conditions by parenteral administration, aerosol or insufflation | E. R. SQUIBB & SONS, INC. (US) | 1981-08-04 | — | — | US | disclosed |