Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26601315 | 0.87 | BRAF (0.40) | ALDH1A1POLBADORA3KDM4EMEN1 | |
| SCHEMBL31461675 | 0.82 | RAB9A (0.46) | SMN1; SMN2NPC1RAB9AALDH1A1POLB | |
| SCHEMBL31461671 | 0.77 | ADORA3 (0.48) | ADORA3KDM4EMEN1KMT2A | |
| SCHEMBL31461742 | 0.77 | RAB9A (0.38) | SMN1; SMN2NPC1RAB9AALDH1A1POLB | |
| SCHEMBL31461716 | 0.76 | SLC6A9 (0.39) | — | |
| SCHEMBL11387752 | 0.71 | ALDH1A1 (0.44) | ALDH1A1ADORA3KDM4EMEN1KMT2A | |
| SCHEMBL11406627 | 0.70 | ADORA3 (0.47) | SMN1; SMN2ALDH1A1ADORA3HTTLMNA | |
| SCHEMBL31461655 | 0.69 | HPGD (0.48) | SMN1; SMN2NPC1RAB9AALDH1A1POLB | |
| SCHEMBL26601373 | 0.69 | NPC1 (0.40) | SMN1; SMN2NPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL31461720 | 0.69 | HCN1 (0.41) | SMN1; SMN2ALDH1A1POLBKDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025024543-A1 | TRICYCLIC UBE2K MODULATORS AND METHODS FOR THEIR USE | BPGBIO, INC. (US) | 2025-01-30 | — | — | WO | disclosed |