Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.43 |
| ▸ | PRKCA | P17252 | 2/20 | 0.42 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.42 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.42 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.40 |
| ▸ | NAAA | Q02083 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11388485 | 1.00 | ALOX5 (0.43) | ALOX5PRKCAPRKCDS1PR5PARP10 | |
| SCHEMBL11388488 | 1.00 | ALOX5 (0.43) | ALOX5PRKCAPRKCDS1PR5PARP10 | |
| SCHEMBL11395971 | 0.89 | S1PR5 (0.47) | ALOX5PRKCAPRKCDS1PR5PARP10 | |
| SCHEMBL11395972 | 0.89 | S1PR5 (0.47) | ALOX5PRKCAPRKCDS1PR5PARP10 | |
| Hydrochloric Acid SCHEMBL11399433 | 0.89 | S1PR5 (0.46) | ALOX5PRKCAPRKCDS1PR5PARP10 | |
| Hydrochloric Acid SCHEMBL11399418 | 0.89 | S1PR5 (0.46) | ALOX5PRKCAPRKCDS1PR5PARP10 | |
| SCHEMBL11395692 | 0.88 | LTA4H (0.48) | ALOX5PRKCAPRKCDS1PR5 | |
| SCHEMBL11395689 | 0.88 | LTA4H (0.48) | ALOX5PRKCAPRKCDS1PR5 | |
| SCHEMBL11395691 | 0.88 | LTA4H (0.48) | ALOX5PRKCAPRKCDS1PR5 | |
| SCHEMBL11392784 | 0.86 | SRD5A2 (0.40) | ALOX5S1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4243587-A | CYCLIZING A 3-ACYLAMINO-4A-ACETOXYAZETIDINONE ESTER WITH HYDROCHLORIC ACID TO OBTAIN THE 4-OXA-2,6-DIAZABICYCLO(3.2.0)HEPTANE | ELI LILLY AND COMPANY (US) | 1981-01-06 | — | — | US | disclosed |
| US-4226767-A | NOCARDICIN | ELI LILLY AND COMPANY (US) | 1980-10-07 | — | — | US | disclosed |
| US-4180507-A | NOCARDICIN INTERMEDIATE | ELI LILLY AND COMPANY (US) | 1979-12-25 | — | — | US | disclosed |
| US-4127568-A | Process for 3β-aminoazetidin-2-ones | ELI LILLY AND COMPANY (US) | 1978-11-28 | — | — | US | disclosed |