Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 1/20 | 0.47 |
| ▸ | GSK3B | P49841 | 6/20 | 0.42 |
| ▸ | STK10 | O94804 | 3/20 | 0.41 |
| ▸ | SLK | Q9H2G2 | 3/20 | 0.41 |
| ▸ | GSK3A | P49840 | 3/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.37 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GMNN | O75496 | 1/20 | 0.36 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11784246 | 0.78 | DNM1 (0.42) | DNM1GSK3BSTK10SLKGSK3A | |
| SCHEMBL15020452 | 0.77 | DNM1 (0.42) | DNM1GSK3BSTK10SLKGSK3A | |
| SCHEMBL15020067 | 0.77 | DNM1 (0.42) | DNM1GSK3BSTK10SLKGSK3A | |
| SCHEMBL15020065 | 0.77 | DNM1 (0.42) | DNM1GSK3BSTK10SLKGSK3A | |
| SCHEMBL15039580 | 0.77 | DNM1 (0.42) | DNM1GSK3BSTK10SLKGSK3A | |
| SCHEMBL11677342 | 0.76 | DNM1 (0.50) | DNM1GSK3BHSD17B10ALDH1A1MAPT | |
| SCHEMBL15020450 | 0.74 | DNM1 (0.39) | DNM1GSK3BSTK10SLKGSK3A | |
| SCHEMBL17745046 | 0.74 | DNM1 (0.39) | DNM1GSK3BSTK10SLKGSK3A | |
| SCHEMBL11390354 | 0.74 | DNM1 (0.55) | DNM1HSD17B10ALDH1A1LMNAMAPT | |
| SCHEMBL15020488 | 0.73 | DNM1 (0.38) | DNM1GSK3BSTK10SLKGSK3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4260749-A | HAIR DYES | L'OREAL (FR) | 1981-04-07 | — | — | US | disclosed |
| US-4204059-A | HAIR DYES | L'OREAL (FR) | 1980-05-20 | — | — | US | disclosed |
| US-4084052-A | HAIR DYES | L'OREAL (FR) | 1978-04-11 | — | — | US | disclosed |
| US-4023926-A | Diaminobenzoquinones in hair dye compositions | SOCIETE ANONYME DITE: L'OREAL (FR) | 1977-05-17 | — | — | US | disclosed |