Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | BRAF | P15056 | 4/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.39 |
| ▸ | CDC25B | P30305 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23831114 | 0.90 | DNM1 (0.60) | DNM1CYP3A4TSHRBRAFHDAC6 | |
| SCHEMBL30193381 | 0.90 | DNM1 (0.60) | DNM1CYP3A4TSHRBRAFHDAC6 | |
| SCHEMBL29098362 | 0.78 | CYP3A4 (0.50) | DNM1CYP3A4TSHRBRAFHDAC6 | |
| SCHEMBL11388748 | 0.76 | DNM1 (0.47) | DNM1CYP3A4TSHRGSK3BKMT2A | |
| SCHEMBL11390354 | 0.73 | DNM1 (0.55) | DNM1CYP3A4RAPGEF4KMT2AALDH1A1 | |
| SCHEMBL30026816 | 0.71 | CYP3A4 (0.86) | CYP3A4TSHRBRAFHDAC6RAPGEF4 | |
| SCHEMBL1389429 | 0.71 | CYP3A4 (0.86) | CYP3A4TSHRBRAFHDAC6RAPGEF4 | |
| SCHEMBL13302358 | 0.69 | CYP3A4 (0.82) | CYP3A4TSHRBRAFHDAC6RAPGEF4 | |
| SCHEMBL23831115 | 0.69 | CDC25B (0.71) | GSK3BKMT2AALDH1A1MAP2K7CDC25B | |
| SCHEMBL30193901 | 0.69 | CDC25B (0.71) | GSK3BKMT2AALDH1A1MAP2K7CDC25B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4023926-A | Diaminobenzoquinones in hair dye compositions | SOCIETE ANONYME DITE: L'OREAL (FR) | 1977-05-17 | — | — | US | disclosed |