Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS | O95271 | 1/20 | 0.58 |
| ▸ | GUSB | P08236 | 5/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.47 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | PARP1 | P09874 | 1/20 | 0.47 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.47 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11382413 | 0.91 | GUSB (0.59) | TNKSGUSBMEN1POLBTSHR | |
| SCHEMBL11375840 | 0.89 | ALDH1A1 (0.58) | TNKSGUSBMEN1POLBTSHR | |
| SCHEMBL11556023 | 0.86 | GUSB (0.51) | TNKSGUSBMEN1POLBTSHR | |
| SCHEMBL183430 | 0.82 | GUSB (0.59) | TNKSGUSBCYP1A1CYP1B1CYP1A2 | |
| SCHEMBL1622681 | 0.81 | CSNK2A2 (0.64) | TNKSGUSBCYP1A1CYP1B1CYP1A2 | |
| SCHEMBL17786634 | 0.81 | GUSB (0.58) | TNKSGUSBCYP1A1CYP1B1CYP1A2 | |
| SCHEMBL11549248 | 0.81 | GUSB (0.56) | GUSBMEN1POLBTSHRKMT2A | |
| SCHEMBL29740691 | 0.80 | GUSB (0.78) | TNKSGUSBCYP1A1CYP1B1CYP1A2 | |
| SCHEMBL1084872 | 0.80 | GUSB (0.78) | TNKSGUSBCYP1A1CYP1B1CYP1A2 | |
| SCHEMBL11553644 | 0.79 | ALDH1A1 (0.53) | GUSBMEN1POLBTSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4251531-A | ANTIALLERGENS | FARMITALIA CARLO ERBA S.P.A. (IT) | 1981-02-17 | — | — | US | disclosed |