Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 2/20 | 0.56 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.50 |
| ▸ | DRD3 | P35462 | 1/20 | 0.50 |
| ▸ | LTA4H | P09960 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | RAD52 | P43351 | 1/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.46 |
| ▸ | HTR5A | P47898 | 1/20 | 0.46 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11387442 | 0.92 | XDH (0.54) | XDHSIGMAR1HRH3LTA4HL3MBTL1 | |
| SCHEMBL11389372 | 0.91 | HRH3 (0.55) | XDHSIGMAR1HRH3MAOB | |
| SCHEMBL11383329 | 0.88 | RAD52 (0.61) | SIGMAR1LTA4HKMT2AMEN1L3MBTL1 | |
| SCHEMBL1795765 | 0.85 | SIGMAR1 (0.56) | SIGMAR1HRH3LTA4HKDM4EMAOB | |
| SCHEMBL1795398 | 0.85 | SIGMAR1 (0.53) | SIGMAR1HRH3KDM4EMAOB | |
| SCHEMBL11383666 | 0.85 | HRH3 (0.63) | XDHSIGMAR1HRH3MAOB | |
| SCHEMBL11384862 | 0.84 | XDH (0.57) | XDHHRH3LTA4HL3MBTL1MAOB | |
| SCHEMBL1793194 | 0.84 | SIGMAR1 (0.57) | SIGMAR1HRH3MAOB | |
| SCHEMBL1795459 | 0.83 | SIGMAR1 (0.52) | XDHSIGMAR1HRH3MAOB | |
| SCHEMBL1794312 | 0.83 | SIGMAR1 (0.49) | XDHSIGMAR1HRH3MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4244954-A | Acridine compounds and methods of combatting viruses with them | STERLING DRUG INC. (US) | 1981-01-13 | — | — | US | disclosed |
| US-4150134-A | Aminoalkoxy substituted 9(aryl or aralkyl)-acridines | STERLING DRUG INC. (US) | 1979-04-17 | — | — | US | disclosed |