Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.37 |
| ▸ | HTR7 | P34969 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.35 |
| ▸ | ADCY8 | P40145 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11884053 | 0.86 | AKR1B1 (0.46) | MEN1KMT2AAKR1B1HTR7IDO1 | |
| SCHEMBL9539722 | 0.70 | AKR1B1 (0.50) | AKR1B1HTR7IDO1MAPTPGR | |
| SCHEMBL21939397 | 0.69 | AKR1B1 (0.41) | MEN1KMT2AAKR1B1HTR7IDO1 | |
| SCHEMBL4594261 | 0.69 | AKR1B1 (0.43) | MEN1KMT2AAKR1B1HTR7IDO1 | |
| SCHEMBL11388713 | 0.68 | MDM2 (0.46) | MEN1KMT2AAKR1B1IDO1 | |
| SCHEMBL9539014 | 0.68 | AKR1B1 (0.40) | MEN1KMT2AAKR1B1HTR7IDO1 | |
| SCHEMBL9539047 | 0.68 | AKR1B1 (0.48) | AKR1B1HTR7IDO1MAPTCHRM1 | |
| SCHEMBL11882562 | 0.68 | MDM2 (0.54) | MEN1KMT2AAKR1B1IDO1 | |
| SCHEMBL9541565 | 0.66 | AKR1B1 (0.51) | MEN1KMT2AAKR1B1IDO1MAPT | |
| SCHEMBL2467583 | 0.66 | CYP46A1 (0.35) | MEN1KMT2AAKR1B1IDO1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4258187-A | REACTING 2-AMINO-BENZOPHENONE DERIVATIVES WITH A HYDROXYLAMINE SALT | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-03-24 | — | — | US | disclosed |
| EP-0000149-A1 | Process for preparing quinazolinone oxides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1979-01-10 | — | — | EP | disclosed |