Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 5/20 | 0.46 |
| ▸ | IDO1 | P14902 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | ADCY8 | P40145 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 4/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 2/20 | 0.35 |
| ▸ | MGAM | O43451 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SI | P14410 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11390102 | 0.86 | MEN1 (0.39) | AKR1B1IDO1MEN1KMT2AMAPT | |
| SCHEMBL9539722 | 0.80 | AKR1B1 (0.50) | AKR1B1IDO1MAPTBRD4HTR7 | |
| SCHEMBL9539047 | 0.78 | AKR1B1 (0.48) | AKR1B1IDO1MAPTBRD4HTR7 | |
| SCHEMBL9541565 | 0.76 | AKR1B1 (0.51) | AKR1B1IDO1MEN1KMT2AMAPT | |
| SCHEMBL9539767 | 0.72 | AKR1B1 (0.48) | AKR1B1IDO1MEN1KMT2AMAPT | |
| SCHEMBL9539996 | 0.72 | AKR1B1 (0.48) | AKR1B1IDO1MEN1KMT2AMAPT | |
| SCHEMBL9571341 | 0.72 | AKR1B1 (0.45) | AKR1B1IDO1MEN1KMT2AMAPT | |
| SCHEMBL9539756 | 0.72 | AKR1B1 (0.56) | AKR1B1IDO1MEN1KMT2AHTR7 | |
| SCHEMBL11882562 | 0.72 | MDM2 (0.54) | AKR1B1IDO1MEN1KMT2AMDM2 | |
| SCHEMBL4594261 | 0.71 | AKR1B1 (0.43) | AKR1B1IDO1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3865827-A | Process for producing quanazolinone derivatives | SUMIMATO CHEMICAL COMPANY LIMI | 1975-02-11 | — | — | US | disclosed |