Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 2/20 | 0.50 |
| ▸ | KLK1 | P06870 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 3/20 | 0.43 |
| ▸ | PLAU | P00749 | 3/20 | 0.43 |
| ▸ | PLAT | P00750 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.41 |
| ▸ | PLG | P00747 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11388122 | 0.83 | MEN1 (0.43) | ELANEKLK1TP53F2PLAU | |
| SCHEMBL11400014 | 0.81 | ELANE (0.42) | ELANEKLK1TP53F2PLAU | |
| SCHEMBL11398405 | 0.81 | ATM (0.41) | ELANETP53POLBTDP1KMT2A | |
| SCHEMBL11390684 | 0.79 | ELANE (0.45) | ELANEKLK1TP53F2PLAU | |
| SCHEMBL25591711 | 0.78 | ELANE (0.51) | ELANEKLK1NPSR1POLBTDP1 | |
| SCHEMBL10458230 | 0.76 | ELANE (0.47) | ELANEF2PLAUPLATNPSR1 | |
| SCHEMBL11795459 | 0.74 | ELANE (0.47) | ELANEKLK1TP53F2PLAU | |
| SCHEMBL711351 | 0.72 | GAA (0.52) | POLBTDP1KMT2ALMNA | |
| SCHEMBL10876771 | 0.72 | ELANE (0.46) | ELANEKLK1TP53F2PLAU | |
| SCHEMBL12942611 | 0.71 | MTNR1A (0.53) | ELANEF2PLAUPLATNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4258040-A | Cephalosporin compounds | MERCK & CO., INC. (US) | 1981-03-24 | — | — | US | disclosed |
| US-4060687-A | Cephalosporins having a 3-α substituted alkyl grouping | MERCK & CO., INC. (US) | 1977-11-29 | — | — | US | disclosed |
| US-3947413-A | ANTIBIOTICS | MERCK & CO., INC. (US) | 1976-03-30 | — | — | US | disclosed |